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Oxford researchers start new trial on the use of anti-TNF to treat Covid-19 in care homes

Researchers at the University of Oxford are starting a new study to explore the effectiveness of the anti-tumour necrosis factor (anti-TNF) drug adalimumab as a treatment for patients with COVID-19 in the community, especially care homes. The AVID-CC trial, which will be conducted by Oxford Clinical Trials Research Unit (OCTRU), will enrol up to 750 patients from community care settings throughout the UK.

Professor Chris Lavy awarded prestigious honorary fellowship by British Orthopaedic Association

Professor of Orthopaedic and Tropical Surgery and Consultant Orthopaedic and Spine Surgeon Chris Lavy has been awarded a prestigious honorary fellowship by the British Orthopaedic Association (BOA).

Key discovery in Psoriatic Arthritis points way for developing targeted treatments

A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the strongest evidence yet of a single cause for the disease.

Operation Ouch!

CBBC's Operation Ouch have been helping to raise awareness of participation in clinical trials for children.

NEON trial opens to recruitment!

The NEON trial has received OCTRU Green Light approval and is about to open sites to recruitment!

Research success leads to expansion

A new wing is being built to expand the Botnar Research Centre and advance its research into musculoskeletal science and bioengineering technologies.

Patients set to benefit from new guidelines on Artificial Intelligence health solutions

Patients could benefit from a faster and more effective introduction of artificial intelligence (AI) innovations to diagnose and treat disease – thanks to the first international standards for reporting of clinical trials for AI.

Workload linked with an increased risk of knee osteoarthritis

Men and women working in heavy manual occupations are twice as likely to suffer from knee osteoarthritis (OA), the most common joint disorder, compared to those in sedentary occupations according to a new study published in the prestigious journal Seminars in Arthritis and Rheumatism.

WHIST Trial Results

The results of the WHIST trial are in!

Cancer care during COVID-19: lessons from The Oxford Bone Tumour and Soft Tissue Sarcoma service

Sarcoma cancer in Oxford was reorganised during the pandemic. Two studies reveal their success and serve as a guide to other units facing the similar challenge of supporting patients.

Largest global study on hydroxychloroquine safety finds increased cardiovascular risk with azithromycin

The combination of hydroxychloroquine (HCQ) and azithromycin (AZM) has been linked to significant cardiovascular risks including mortality, in the largest safety study ever performed on both HCQ and HCQ+AZM.

Patient’s fundraising takes him to the top of Scafell Pike

Hip replacement patient Nick Birch scales his second mountain to raise funds for University research

IL-22 pathway linked to poor prognosis in colon cancer

Research shows how IL-22 interacts with KRAS mutant tumours to promote excessive growth in colorectal cancer

Pain trajectory defines knee osteoarthritis subgroups

Researchers at NDORMS have identified four subgroups of knee osteoarthritis which will improve patient treatment and drug development.

CRAFFT trial opens to recruitment!

The CRAFFT trial has now opened sites to recruitment.

Grant towards OHDSI Global Research on COVID-19 treatments

An international cohort of OHDSI collaborators obtain a grant from the COVID-19 Therapeutics Accelerator to lead an effort to compare the effectiveness of treatments, including corticosteroids such as dexamethasone, under current evaluation for COVID-19 across an international observational data network.

NDORMS joins collaboration to address COVID-19 in Europe

The collaboration brings the European Health Data & Evidence Network (EHDEN) together with the European Medicines Agency and partners.

Six-month outcomes after treatment for COVID-19 on intensive care units in England

Researchers at the University of Oxford are investigating the long-term health outcomes for patients who have been treated for severe COVID-19 disease in intensive care.

New Associate Professors and University Research Lecturers at NDORMS

The University of Oxford has awarded the title of Associate Professor to seven senior researchers at NDORMS, and three University Research Lecturer titles.

Numerous jobs linked to increased risk of knee osteoarthritis

Stay-at-home parents, cleaners, and blue-collar workers found to be more likely to develop osteoarthritis

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