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New research from a randomised clinical trial published today in The Lancet and funded by the National Institute for Health Research (NIHR) shows that partial knee replacements (PKR) are as good as total knee replacements (TKR), whilst being more cost effective.
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Trials Expertise Session: Effective planning and management of trial sample collections
Tuesday, 04 November 2025, 10.30am to 11.30am
Trials Expertise Session: The role of a Trial Manager in a Trial Management Group (TMG) *online*
Thursday, 12 June 2025, 10am to 11am
Trials Expertise Session: Communication skills in Clinical Trials for Trial Managers *online*
Wednesday, 26 March 2025, 10am to 11am
Trials Expertise Session: Site Feasibility Questionnaires (SFQ) & Site selection *Hybrid*
Wednesday, 25 June 2025, 11am to 12pm
Meet the NDORMS team
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David Beard
Professor of Musculoskeletal and Surgical Science
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Loretta Davies
SITU Trials Portfolio Manager (Operational Lead)
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Jonathan Cook
Professor of Clinical Trials & Medical Statistics/OCTRU Deputy Director
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Andrew Price
Professor of Orthopaedics Surgery
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Andrew Carr
Nuffield Professor of Orthopaedics
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David Murray
Professor of Orthopaedic Surgery
Read the paper
The clinical and cost effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised trial.
The Lancet 2019.
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Funded by
