Andrew Carr

• Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

  Quek L. et al, (2016), J Exp Med, 213, 1513 - 1535

• A comparative evaluation of the effect of polymer chemistry and fiber orientation on mesenchymal stem cell differentiation.

  Rowland DC. et al, (2016), J Biomed Mater Res A

• Surrogate markers of long-term outcome in primary total hip arthroplasty: A systematic review.

  Malak TT. et al, (2016), Bone Joint Res, 5, 206 - 214

• Maternal gestational vitamin D supplementation and offspring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial.

  Cooper C. et al, (2016), Lancet Diabetes Endocrinol, 4, 393 - 402

• Dickkopf-3 is upregulated in osteoarthritis and has a chondroprotective role.

  Snelling SJ. et al, (2016), Osteoarthritis Cartilage, 24, 883 - 891

• A review of current surgical practice in the operative treatment of proximal humeral fractures: Does the PROFHER trial demonstrate a need for change?

  Dean BJ. et al, (2016), Bone Joint Res, 5, 178 - 184

• Gene expression profiles of changes underlying different-sized human rotator cuff tendon tears.

  Chaudhury S. et al, (2016), J Shoulder Elbow Surg

• Obesity and the Relative Risk of Knee Replacement Surgery in Patients With Knee Osteoarthritis: A Prospective Cohort Study.

  Leyland KM. et al, (2016), Arthritis Rheumatol, 68, 817 - 825

• H3K27ME3 DEMETHYLASES REGULATE IN VITRO CHONDROGENESIS AND CHONDROCYTE ACTIVITY IN OSTEOARTHRITIS

  Yapp C. et al, (2016), OSTEOARTHRITIS AND CARTILAGE, 24, S181 - S181

• In vitro two-dimensional and three-dimensional tenocyte culture for tendon tissue engineering.

  Qiu Y. et al, (2016), J Tissue Eng Regen Med, 10, E216 - E226

• Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England.

  Kendal AR. et al, (2016), Br J Sports Med, 50

• Are inflammatory cells increased in painful human tendinopathy? A systematic review.

  Dean BJ. et al, (2016), Br J Sports Med, 50, 216 - 220

• Translating Regenerative Biomaterials Into Clinical Practice.

  Stace ET. et al, (2016), J Cell Physiol, 231, 36 - 49

• The response of tenocytes to commercial scaffolds used for rotator cuff repair.

  Smith RD. et al, (2016), Eur Cell Mater, 31, 107 - 118

• The response of tenocytes to commercial scaffolds used for rotator cuff repair.

  Smith RD. et al, (2016), Eur Cell Mater, 31, 107 - 118

• The Effects of Glucocorticoid on Tendon and Tendon Derived Cells.

  Dean BJ. and Carr AJ., (2016), Adv Exp Med Biol, 920, 239 - 246

• H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis.

  Yapp C. et al, (2016), Arthritis Res Ther, 18

• Feasibility of surgical randomised controlled trials with a placebo arm: a systematic review.

  Wartolowska K. et al, (2016), BMJ Open, 6

• Comparison of transforming growth factor beta expression in healthy and diseased human tendon.

  Goodier HC. et al, (2016), Arthritis Res Ther, 18

• A survey on beliefs and attitudes of trainee surgeons towards placebo.

  Baldwin MJ. et al, (2016), BMC Surg, 16

• Platelet-Rich Plasma Injection With Arthroscopic Acromioplasty for Chronic Rotator Cuff Tendinopathy: A Randomized Controlled Trial.

  Carr AJ. et al, (2015), Am J Sports Med, 43, 2891 - 2897

• Inflammation activation and resolution in human tendon disease.

  Dakin SG. et al, (2015), Science Translational Medicine, 7

• Inflammation activation and resolution in human tendon disease.

  Dakin SG. et al, (2015), Sci Transl Med, 7

• Lovastatin-Mediated Changes in Human Tendon Cells.

  Kuzma-Kuzniarska M. et al, (2015), J Cell Physiol, 230, 2543 - 2551

• In vitro effects of glutamate and N-methyl-D-aspartate receptor (NMDAR) antagonism on human tendon derived cells.

  Dean BJ. et al, (2015), J Orthop Res, 33, 1515 - 1522

• In vitro effects of glutamate and N-methyl- d -aspartate receptor (NMDAR) antagonism on human tendon derived cells

  Dean BJF. et al, (2015), Journal of Orthopaedic Research, 33, 1515 - 1522

• Clinical effectiveness and cost-effectiveness of open and arthroscopic rotator cuff repair [the UK Rotator Cuff Surgery (UKUFF) randomised trial].

  Carr AJ. et al, (2015), Health Technol Assess, 19, 1 - 218

• Arthroscopic surgery for degenerative knee: Overused, ineffective, and potentially harmful

  Carr A., (2015), BRITISH JOURNAL OF SPORTS MEDICINE, 49

• A layered electrospun and woven surgical scaffold to enhance endogenous tendon repair.

  Hakimi O. et al, (2015), Acta Biomater, 26, 124 - 135

• Variations In Good Patient Reported Outcomes After Total Knee Arthroplasty.

  Kiran A. et al, (2015), J Arthroplasty, 30, 1364 - 1371

• Osteoarthritis.

  Glyn-Jones S. et al, (2015), Lancet, 386, 376 - 387

• Osteoarthritis

  Glyn-Jones S. et al, (2015), The Lancet, 386, 376 - 387

• Cell proliferation is a key determinant of the outcome of FOXO3a activation.

  Poulsen RC. et al, (2015), Biochem Biophys Res Commun, 462, 78 - 84

• Fabrication of continuous electrospun filaments with potential for use as medical fibres.

  Mouthuy PA. et al, (2015), Biofabrication, 7

• Cell proliferation is a key determinant of the outcome of FOXO3a activation.

  Hulley PA. et al, (2015), Biochem Biophys Res Commun.

• VOLUMETRIC PERI-PROSTHETIC OSTEOLYSIS IN TOTAL HIP ARTHROPLASTY MEASURED USING COMPUTED TOMOGRAPHY - A 12 YEAR PROSPECTIVE DOUBLE BLIND RANDOMIZED CONTROLLED TRIAL

  Broomfield JA. et al, (2015), OSTEOARTHRITIS AND CARTILAGE, 23, A409 - A410

• PATHOGENESIS OF CAM MORPHOLOGY IN ENGLISH PREMIERSHIP FOOTBALLERS

  Palmer AJ. et al, (2015), OSTEOARTHRITIS AND CARTILAGE, 23, A57 - A58

• Preclinical target validation using patient-derived cells.

  Edwards AM. et al, (2015), Nat Rev Drug Discov, 14, 149 - 150

• Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study.

  Prieto-Alhambra D. et al, (2015), Ann Rheum Dis, 74, 557 - 563

• Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

  French A. et al, (2015), Stem Cells Transl Med, 4, 217 - 223

• Advances in biology and mechanics of rotator cuff repair.

  Lorbach O. et al, (2015), Knee Surg Sports Traumatol Arthrosc, 23, 530 - 541

• Advances in arthroscopy-indications and therapeutic applications.

  Carr AJ. et al, (2015), Nat Rev Rheumatol, 11, 77 - 85

• Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies.

  Silva M. et al, (2015), Cell Stem Cell, 16, 13 - 17

• The CSAW Study (Can Shoulder Arthroscopy Work?) - a placebo-controlled surgical intervention trial assessing the clinical and cost effectiveness of arthroscopic subacromial decompression for shoulder pain: study protocol for a randomised controlled trial.

  Beard D. et al, (2015), Trials, 16

• Meaningful changes for the Oxford hip and knee scores after joint replacement surgery.

  Beard DJ. et al, (2015), J Clin Epidemiol, 68, 73 - 79

• Differences in glutamate receptors and inflammatory cell numbers are associated with the resolution of pain in human rotator cuff tendinopathy.

  Dean BJ. et al, (2015), Arthritis Res Ther, 17

• Arthroscopic surgery for degenerative knee.

  Carr A., (2015), BMJ, 350

• Advances in arthroscopy - Indications and therapeutic applications

  Carr AJ. et al, (2015), Nature Reviews Rheumatology, 11, 77 - 85

• A layered electrospun and woven surgical scaffold to enhance endogenous tendon repair

  Hakimi O. et al, (2015), Acta Biomaterialia, 26, 124 - 135

• Review of clinical outcomes-based anchors of minimum clinically important differences in hip and knee registry-based reports and publications.

  Romero L. et al, (2014), J Bone Joint Surg Am, 96 Suppl 1, 98 - 103

• Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34-Human Acute Myeloid Leukemia

  Quek L. et al, (2014), BLOOD, 124

• The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study.

  Panoutsopoulou K. et al, (2014), Ann Rheum Dis, 73, 2082 - 2086

• Response to letter to the editor: "Cam impingement: defining the presence of a cam deformity by the alpha angle data from the CHECK cohort an Chingford cohort".

  Agricola R. et al, (2014), Osteoarthritis Cartilage, 22, 2095 - 2096

• Glucocorticoids induce specific ion-channel-mediated toxicity in human rotator cuff tendon: a mechanism underpinning the ultimately deleterious effect of steroid injection in tendinopathy?

  Dean BJ. et al, (2014), Br J Sports Med, 48, 1620 - 1626

• Development of a refined tenocyte expansion culture technique for tendon tissue engineering.

  Qiu Y. et al, (2014), J Tissue Eng Regen Med, 8, 955 - 962

• A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.

  Evangelou E. et al, (2014), Ann Rheum Dis, 73, 2130 - 2136

• Changing the mindset in life sciences toward translation: a consensus.

  Duda GN. et al, (2014), Sci Transl Med, 6

• Protocol for the Femoroacetabular Impingement Trial (FAIT): a multi-centre randomised controlled trial comparing surgical and non-surgical management of femoroacetabular impingement.

  Palmer AJ. et al, (2014), Bone Joint Res, 3, 321 - 327

• Subclinical deformities of the hip are significant predictors of radiographic osteoarthritis and joint replacement in women. A 20 year longitudinal cohort study.

  Thomas GE. et al, (2014), Osteoarthritis Cartilage, 22, 1504 - 1510

• Distribution and expression of type VI collagen and elastic fibers in human rotator cuff tendon tears.

  Thakkar D. et al, (2014), Connect Tissue Res, 55, 397 - 402

• Up-regulation of Glutamate in Painful Human Supraspinatus Tendon Tears.

  Franklin SL. et al, (2014), Am J Sports Med, 42, 1955 - 1962

• Primary hip replacement prostheses and their evidence base: systematic review of literature.

  Kynaston-Pearson F. et al, (2014), Br J Sports Med, 48

• Effect of tear size, corticosteroids and subacromial decompression surgery on the hierarchical structural properties of torn supraspinatus tendons.

  Tilley JM. et al, (2014), Bone Joint Res, 3, 252 - 261

• Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence.

  Poulsen RC. et al, (2014), Ann Rheum Dis, 73, 1405 - 1413

• Classification of rotator cuff tendinopathy using high definition ultrasound.

  Hinsley H. et al, (2014), Muscles Ligaments Tendons J, 4, 391 - 397

• THE ASSESSMENT OF SHOULDER INSTABILITY: THE DEVELOPMENT AND VALIDATION OF A QUESTIONNAIRE - THE OXFORD SHOULDER INSTABILITY SCORE (OSIS)

  Dawson J. et al, (2014), VALUE IN HEALTH, 17, A51 - A51

• Renal development and cystic diseases.

  Cabrera-López C. et al, (2014), Nephrol Dial Transplant, 29 Suppl 3, iii73 - iii78

• Protocol for the United Kingdom Rotator Cuff Study (UKUFF): a randomised controlled trial of open and arthroscopic rotator cuff repair.

  Carr AJ. et al, (2014), Bone Joint Res, 3, 155 - 160

• THE NEUROHISTOLOGY OFPAINFUL AND PAIN-FREE ROTATOR CUFF TENDONS: A CASE CONTROL STUDY

  Dean BJ. et al, (2014), OSTEOARTHRITIS AND CARTILAGE, 22, S420 - S420

• PELVIS IS SUPERIOR TO FEMUR AND TIBIA AS A SOURCE FOR MINIMALLY MANIPULATED MESENCHYMAL STEM CELLS

  Davies BM. et al, (2014), OSTEOARTHRITIS AND CARTILAGE, 22, S443 - S444

• NEW FUNCTIONAL MICROSATELLITE ASSOCIATED WITH OSTEOARTHRITIS SUSCEPTIBILITY

  Vidal-Bralo L. et al, (2014), OSTEOARTHRITIS AND CARTILAGE, 22, S232 - S233

• EPIGENETIC MODIFYING COMPOUNDS ALTER ACTIVITY OF PRIMARY HUMAN ARTICULAR CHONDROCYTES AND MESENCHYMAL STEM CELLS UNDERGOING CHONDROGENESIS

  Snelling S. et al, (2014), OSTEOARTHRITIS AND CARTILAGE, 22, S141 - S141

• Characterisation of tendons at different length scales using atomic force microscopy and polarised light microscopy may provide insight into tendon disease

  Tilley JMR. et al, (2014), Atomic Force Microscopy (AFM): Principles, Modes of Operation and Limitations, 177 - 192

• Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies.

  Rodriguez-Fontenla C. et al, (2014), Arthritis Rheumatol, 66, 940 - 949

• Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure.

  Hulley PA. et al, (2014), Cell Death Dis.

• The risks and benefits of glucocorticoid treatment for tendinopathy: a systematic review of the effects of local glucocorticoid on tendon.

  Dean BJ. et al, (2014), Semin Arthritis Rheum, 43, 570 - 576

• Cam impingement: defining the presence of a cam deformity by the alpha angle: data from the CHECK cohort and Chingford cohort.

  Agricola R. et al, (2014), Osteoarthritis Cartilage, 22, 218 - 225

• A gene expression study of normal and damaged cartilage in anteromedial gonarthrosis, a phenotype of osteoarthritis.

  Snelling S. et al, (2014), Osteoarthritis Cartilage, 22, 334 - 343

• Use of placebo controls in the evaluation of surgery: systematic review.

  Wartolowska K. et al, (2014), BMJ, 348

• Temporal trends and geographical variation in the use of subacromial decompression and rotator cuff repair of the shoulder in England.

  Judge A. et al, (2014), Bone Joint J, 96-B, 70 - 74

• Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study.

  Davies BM. et al, (2014), J Tissue Eng, 5

• Neuronal pathways in tendon healing and tendinopathy--update.

  Ackermann PW. et al, (2014), Front Biosci (Landmark Ed), 19, 1251 - 1278

• European musculoskeletal health and mobility in Horizon 2020: Setting priorities for musculoskeletal research and innovation.

  Lidgren L. et al, (2014), Bone Joint Res, 3, 48 - 50

• Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure.

  Poulsen RC. et al, (2014), Cell Death Dis, 5

• Baseline bone mineral density and boneturnover in pre-operative hip and knee arthroplasty patients.

  James SJ. et al, (2014), Bone Joint Res, 3, 14 - 19

• Attitudes and beliefs about placebo surgery among orthopedic shoulder surgeons in the United Kingdom.

  Wartolowska K. et al, (2014), PLoS One, 9

• Advances in the understanding of tendinopathies: a report on the Second Havemeyer Workshop on equine tendon disease.

  Smith R. et al, (2014), Equine Vet J, 46, 4 - 9

• Imaging and modeling collagen architecture from the nano to micro scale.

  Brown CP. et al, (2013), Biomed Opt Express, 5, 233 - 243

• The incidence of pseudotumour in metal-on-metal hip resurfacing and the results of a screening tool for patient recall

  Erturan G. et al, (2013), Total Hip Arthroplasty: Tribological Considerations and Clinical Consequences, 75 - 83

• The implementation of novel collaborative structures for the identification and resolution of barriers to pluripotent stem cell translation.

  Brindley DA. et al, (2013), Stem Cells Dev, 22 Suppl 1, 63 - 72

• Why does my shoulder hurt? A review of the neuroanatomical and biochemical basis of shoulder pain.

  Dean BJ. et al, (2013), Br J Sports Med, 47, 1095 - 1104

• Epigenetic modifying compounds alter activity of primary human articular chondrocytes and mesenchymal stem cells undergoing chondrogenesis

  Snelling SJB. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A16 - A16

• Cam impingement of the hip: a risk factor for hip osteoarthritis.

  Agricola R. et al, (2013), Nat Rev Rheumatol, 9, 630 - 634

• Understanding of regional variation in the use of surgery.

  Birkmeyer JD. et al, (2013), Lancet, 382, 1121 - 1129

• The peripheral neuronal phenotype is important in the pathogenesis of painful human tendinopathy: a systematic review.

  Dean BJ. et al, (2013), Clin Orthop Relat Res, 471, 3036 - 3046

• Repairing damaged tendon and muscle: are mesenchymal stem cells and scaffolds the answer?

  Davies BM. et al, (2013), Regen Med, 8, 613 - 630

• Synthetic and degradable patches: an emerging solution for rotator cuff repair.

  Hakimi O. et al, (2013), Int J Exp Pathol, 94, 287 - 292

• Structural adaptations of rotator cuff tendons associated with degeneration, tearing and treatment highlight the need for improved tendon diagnostics and early intervention strategies

  Tilley JMR. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A5 - A6

• Short term tissue response to current treatments for rotator cuff tendinopathy

  Murphy RJ. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A9 - A10

• Rotator cuff tendinopathy: immunohistochemical changes across the spectrum of pathology

  Murphy RJ. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A9 - A9

• Glucocorticoids induce senescence and alter matrix protein expression in primary human tenocytes

  Poulsen RC. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A20 - A21

• Could topographical variations in the structural adaptations of rotator cuff tendons play an important role in degeneration and tearing?

  Tilley JMR. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A7 - A8

• Age related change in the supraspinatus tendon

  Murphy RJ. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A9 - A9

• The pattern of cartilage damage in antero-medial osteoarthritis of the knee and its relationship to the anterior cruciate ligament

  Rout R. et al, (2013), Journal of Orthopaedic Research, 31, 908 - 913

• The pattern of cartilage damage in antero-medial osteoarthritis of the knee and its relationship to the anterior cruciate ligament.

  Rout R. et al, (2013), J Orthop Res, 31, 908 - 913

• Short term tissue response to current treatments for rotator cuff tendinopathy.

  Murphy RJ. et al, (2013), Br J Sports Med, 47

• Rotator cuff tendinopathy: immunohistochemical changes across the spectrum of pathology.

  Murphy RJ. et al, (2013), Br J Sports Med, 47

• Non-invasive imaging of cartilage in early osteoarthritis.

  Palmer AJ. et al, (2013), Bone Joint J, 95-B, 738 - 746

• Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data.

  Elliott KS. et al, (2013), Ann Rheum Dis, 72, 935 - 941

• Age-related changes in the supraspinatus tendon.

  Murphy RJ. et al, (2013), Br J Sports Med, 47

• Coxa recta, coxa profunda and abductor ratio: hip morphology variants compared in an arthroplasty and control population.

  de Boer SF. et al, (2013), Hip Int, 23, 287 - 292

• Motor control retraining exercises for shoulder impingement: effects on function, muscle activation, and biomechanics in young adults.

  Worsley P. et al, (2013), J Shoulder Elbow Surg, 22, e11 - e19

• MORTALITY FOLLOWING ELECTIVE TOTAL HIP REPLACEMENT AND HIP RESURFACING

  Judge A. et al, (2013), OSTEOARTHRITIS AND CARTILAGE, 21, S162 - S162

• MORTALITY FOLLOWING ELECTIVE TOTAL HIP REPLACEMENT AND HIP RESURFACING

  Kendal A. et al, (2013), RHEUMATOLOGY, 52, 41 - 42

• Glucocorticoids induce senescence in primary human tenocytes: in vitro and in vivo evidence

  Poulsen RC. et al, (2013), Osteoarthritis and Cartilage, 21, S63 - S64

• EPIGENETIC MODIFYING COMPOUNDS AFFECT THE ACTIVITY OF PRIMARY HUMAN ARTICULAR CHONDROCYTES AND MESENCHYMAL STEM CELLS UNDERGOING CHONDROGENESIS

  Snelling S. et al, (2013), OSTEOARTHRITIS AND CARTILAGE, 21, S131 - S131

• AGEING AND OSTEOARTHRITIS MARKERS IDENTIFIED BY MALDI IMAGING MASS SPECTROMETRY

  Poulsen RC. et al, (2013), OSTEOARTHRITIS AND CARTILAGE, 21, S63 - S64

• An independent learning method for orthopaedic surgeons performing shoulder ultrasound to identify full-thickness tears of the rotator cuff.

  Murphy RJ. et al, (2013), J Bone Joint Surg Am, 95, 266 - 272

• The hereditary predisposition to hip osteoarthritis and its association with abnormal joint morphology.

  Pollard TC. et al, (2013), Osteoarthritis Cartilage, 21, 314 - 321

• The feasibility of performing a randomised controlled trial for femoroacetabular impingement surgery.

  Palmer AJ. et al, (2013), Bone Joint Res, 2, 33 - 40

• Glucocorticoids induce senescence and alter matrix protein expression in primary human tenocytes

  Poulsen RC. et al, (2013), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 94, A9 - A10

• Total or Partial Knee Arthroplasty Trial - TOPKAT: study protocol for a randomised controlled trial.

  Beard D. et al, (2013), Trials, 14

• Primary hip replacement prostheses and their evidence base: systematic review of literature.

  Kynaston-Pearson F. et al, (2013), BMJ, 347

• PARot--assessing platelet-rich plasma plus arthroscopic subacromial decompression in the treatment of rotator cuff tendinopathy: study protocol for a randomized controlled trial.

  Carr A. et al, (2013), Trials, 14

• No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls.

  Hudson G. et al, (2013), Ann Rheum Dis, 72, 136 - 139

• Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.

  Kendal AR. et al, (2013), BMJ, 347

• Development of a refined tenocyte differentiation culture technique for tendon tissue engineering.

  Qiu Y. et al, (2013), Cells Tissues Organs, 197, 27 - 36

• Development of a refined tenocyte differentiation culture technique for tendon tissue engineering (vol 197, pg 27, 2013)

  Qiu Y. et al, (2013), CELLS TISSUES ORGANS, 198, 469 - 469

• Corticosteroid injection for shoulder pain: single-blind randomized pilot trial in primary care.

  Holt TA. et al, (2013), Trials, 14

• A population-based survival analysis describing the association of body mass index on time to revision for total hip and knee replacements: results from the UK general practice research database.

  Culliford D. et al, (2013), BMJ Open, 3

• Specificity and responsiveness of patient-reported and clinician-rated outcome measures in the context of elbow surgery, comparing patients with and without rheumatoid arthritis.

  Dawson J. et al, (2012), Orthop Traumatol Surg Res, 98, 652 - 658

• Spécificité et impartialité des évaluations de résultats de chirurgie du coude rapportées par le patient ou le clinicien : comparaison suivant l’existence ou non d’une arthrite rhumatoïde

  Dawson J. et al, (2012), Revue de Chirurgie Orthopédique et Traumatologique, 98, 584 - 585

• Predictors of outcomes of total knee replacement surgery.

  Judge A. et al, (2012), Rheumatology (Oxford), 51, 1804 - 1813

• A review of national shoulder and elbow joint replacement registries.

  Rasmussen JV. et al, (2012), J Shoulder Elbow Surg, 21, 1328 - 1335

• Tensile and shear mechanical properties of rotator cuff repair patches.

  Chaudhury S. et al, (2012), J Shoulder Elbow Surg, 21, 1168 - 1176

• Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

  arcOGEN Consortium None. et al, (2012), Lancet, 380, 815 - 823

• Platelet-rich plasma strongly stimulates human tenocyte proliferation and potently up-regulates tenocyte growth factor secretion

  Franklin SL. et al, (2012), INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 93, A17 - A17

• Change in body mass index during middle age affects risk of total knee arthoplasty due to osteoarthritis: a 19-year prospective study of 1003 women.

  Nicholls AS. et al, (2012), Knee, 19, 316 - 319

• Orthopaedic trial networks.

  Rangan A. et al, (2012), J Bone Joint Surg Am, 94 Suppl 1, 97 - 100

• A systematic review of the histological and molecular changes in rotator cuff disease.

  Dean BJ. et al, (2012), Bone Joint Res, 1, 158 - 166

• Proliferation and differentiation of human tenocytes in response to platelet rich plasma: an in vitro and in vivo study.

  Wang X. et al, (2012), J Orthop Res, 30, 982 - 990

• ASSOCIATION OF A BMP5 MICROSATELLITE WITH KNEE OSTEOARTHRITIS

  Rodriguez-Fontenla C. et al, (2012), ANNALS OF THE RHEUMATIC DISEASES, 71, 473 - 474

• Genetic predisposition to the presence and 5-year clinical progression of hip osteoarthritis.

  Pollard TC. et al, (2012), Osteoarthritis Cartilage, 20, 368 - 375

• CLINICAL OUTCOMES FOLLOWING MOTOR CONTROL REHABILITATION FOR SHOULDER IMPINGEMENT

  Worsley PR. et al, (2012), RHEUMATOLOGY, 51, 95 - 95

• [Adverse reactions of metal/metal hip prostheses - diagnosis and examination].

  Fary C. et al, (2012), Praxis (Bern 1994), 101, 593 - 599

• Knee replacement.

  Carr AJ. et al, (2012), Lancet, 379, 1331 - 1340

• Unerwünschte Reaktionen bei Metall/Metall-Hüftendoprothesen - Diagnostik und Untersuchung

  Fary None. et al, (2012), PRAXIS, 101, 593 - 599

• THE PROTEOME OF YOUNG AND HEALTHY HUMAN HAMSTRING

  Hakimi O. et al, (2012), OSTEOARTHRITIS AND CARTILAGE, 20, S262 - S263

• THE ASSOCIATION BETWEEN HIP MORPHOLOGY AND PAIN - A 20 YEAR LONGITUDINAL STUDY

  Thomas GE. et al, (2012), OSTEOARTHRITIS AND CARTILAGE, 20, S251 - S251

• THE ASSOCIATION BETWEEN HIP MORPHOLGY AND 19-YEAR RISK OF OSTEOARTHRITIS IN THE HIP

  Thomas GE. et al, (2012), OSTEOARTHRITIS AND CARTILAGE, 20, S23 - S24

• THE ASSOCIATION BETWEEN HIP MORPHOLOGY AND END-STAGE OSTEOARTHRITIS AT 12-YEAR FOLLOW UP

  Thomas GE. et al, (2012), OSTEOARTHRITIS AND CARTILAGE, 20, S204 - S204

• PLATELET-RICH PLASMA STIMULATES HUMAN TENOCYTE PROLIFERATION AND POTENTLY UP-REGULATES GROWTH FACTOR PRODUCTION BY TENOCYTES

  Franklin S. et al, (2012), OSTEOARTHRITIS AND CARTILAGE, 20, S249 - S250

• IMPLICATION OF NERVE GROWTH FACTOR AND SUBSTANCE P IN SHOULDER PAIN

  Franklin S. and Carr A., (2012), OSTEOARTHRITIS AND CARTILAGE, 20, S260 - S260

• HIP MORPHOLOGY IN A POPULATION BASED COHORT OF 1003 WOMEN

  Thomas GE. et al, (2012), OSTEOARTHRITIS AND CARTILAGE, 20, S181 - S182

• Differential growth on sutures of tendon cells derived from torn human rotator cuff.

  Hakimi O. et al, (2012), J Biomed Mater Res B Appl Biomater, 100, 685 - 692

• Tenocyte proliferation on collagen scaffolds protects against degradation and improves scaffold properties.

  Tilley JM. et al, (2012), J Mater Sci Mater Med, 23, 823 - 833

• Lessons we can learn from gene expression patterns in rotator cuff tears and tendinopathies.

  Chaudhury S. and Carr AJ., (2012), J Shoulder Elbow Surg, 21, 191 - 199

• A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation.

  Esapa CT. et al, (2012), J Bone Miner Res, 27, 413 - 428

• Regulation of hypoxia-induced cell death in human tenocytes.

  Liang M. et al, (2012), Adv Orthop, 2012

• Motor control retraining exercises for shoulder impingement: effects on function, muscle activation, and biomechanics in young adults

  Worsley P. et al, (2012), Journal of Shoulder and Elbow Surgery

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• PRACTICE POINTER Diagnosing and investigating adverse reactions in metal on metal hip implants

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• BISPHOSPHONATE USE IS ASSOCIATED WITH REDUCED REVISIONS OF LOWER LIMB JOINT (KNEE OR HIP) ARTHROPLASTY: A POPULATION-BASED COHORT STUDY

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• Protection against glucocorticoid-induced damage in human tenocytes by modulation of ERK, Akt, and forkhead signaling.

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• Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

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• Association between bisphosphonate use and implant survival after primary total arthroplasty of the knee or hip: population based retrospective cohort study.

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• Orthopaedic surgery: Current trends and recent innovations

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• Is hypoxia part of the pathology driving vascular remodelling in degenerating rotator cuff tendons?

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• Localized cartilage assessment with three-dimensional dGEMRIC in asymptomatic hips with normal morphology and cam deformity.

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• Using Patient-Reported Outcome Measures (PROMs) Routinely: An Example in the Context of Elective Shoulder Surgery

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• THE arcOGEN CONSORTIUM: STAGE 1 OF A GENOME-WIDE ASSOCIATION SCAN FOR OSTEOARTHRITIS

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• Thalamic atrophy associated with painful osteoarthritis of the hip is reversible after arthroplasty: a longitudinal voxel-based morphometric study.

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• DEEP SEQUENCING OF GDF5 IN OVER 1900 OSTEOARTHRITIS CASES AND CONTROLS REVEALS NOVEL AND POTENTIALLY FUNCTIONAL RARE VARIANTS IN THE PROTEIN CODING AND PROMOTER REGIONS OF THE GENE

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• A MULTICENTER STUDY OF THE ASSOCIATION OF AROMATASE AND ESTROGEN RECEPTOR GENES WITH HIP AND KNEE OSTEOARTHRITIS

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• Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study.

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• ASSESSING THE OUTCOME OF ELBOW SURGERY: DEVELOPMENT, VALIDATION AND RESPONSIVENESS OF THE PATIENT-REPORTED OXFORD ELBOW SCORE (OES)

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• DEVELOPING A PREDICTIVE TOOL FOR OUTCOMES OF TOTAL KNEE REPLACEMENT: SOUTH WEST LONDON ELECTIVE ORTHOPAEDIC CENTRE DATABASE

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• A gene expression profile of damaged vs. undamaged cartilage in anteromedial gonarthrosis

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• Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis.

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• The UKUFF trial and the NIHR comprehensive local research networks

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• A genome-wide association study identifies a common variant near the GRP22 gene as a new locus involved in prevalence and progression of osteoarthritis

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• Retention of arthroscopic shoulder skills learned with use of a simulator. Demonstration of a learning curve and loss of performance level after a time delay.

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• Cell shape change and actin cytoskeleton remodeling drives human tenocytes towards a chondrocytic phenotype

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• The Oxford shoulder score revisited.

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• Frozen shoulder: past, present, and future.

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• Evidence for reduced B-cell progenitors in early (low-risk) myelodysplastic syndrome.

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• Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate.

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• The common HFE variants C282Y and H63D are not associated with primary OA of the hip or knee.

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• Arthroplasty of the elbow in haemophilia - Author's reply

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• Glomus tumor of the scapular region.

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  Woods DA. et al, (1999), J Shoulder Elbow Surg, 8, 291 - 295

• Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.

  Chapman K. et al, (1999), Am J Hum Genet, 65, 167 - 174

• Identification of novel pro-alpha2(IX) collagen gene mutations in two families with distinctive oligo-epiphyseal forms of multiple epiphyseal dysplasia.

  Holden P. et al, (1999), Am J Hum Genet, 65, 31 - 38

• The assessment of shoulder instability. The development and validation of a questionnaire.

  Dawson J. et al, (1999), J Bone Joint Surg Br, 81, 420 - 426

• Refinement of the chromosome 5p locus for familial calcium pyrophosphate dihydrate deposition disease.

  Andrew LJ. et al, (1999), Am J Hum Genet, 64, 136 - 145

• A self-administered questionnaire for assessment of symptoms and function of the shoulder.

  Dawson J. et al, (1998), J Bone Joint Surg Am, 80, 766 - 767

• Soft tissue mass around the shoulder.

  Reid HS. et al, (1998), Ann Rheum Dis, 57, 6 - 8

• Questionnaire on the perceptions of patients about total knee replacement.

  Dawson J. et al, (1998), J Bone Joint Surg Br, 80, 63 - 69

• Primary total hip replacement surgery: a systematic review of outcomes and modelling of cost-effectiveness associated with different prostheses.

  Fitzpatrick R. et al, (1998), Health Technol Assess, 2, 1 - 64

• Patients with primary osteoarthritis show no change with ageing in the number of osteogenic precursors.

  Oreffo RO. et al, (1998), Scand J Rheumatol, 27, 415 - 424

• Identification of five novel mutations in cartilage oligomeric matrix protein gene in pseudoachondroplasia and multiple epiphyseal dysplasia.

  Loughlin J. et al, (1998), Hum Mutat, Suppl 1, S10 - S17

• Synovectomy of the elbow and radial head excision in rheumatoid arthritis. Predictive factors and long-term outcome.

  Gendi NS. et al, (1997), J Bone Joint Surg Br, 79, 918 - 923

• Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis.

  Chitnavis J. et al, (1997), J Bone Joint Surg Br, 79, 660 - 664

• An evaluation of the Constant-Murley shoulder assessment

  Carr AJ., (1997), JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 79B, 696 - 696

• The patient with shoulder problems.

  Carr A., (1997), Practitioner, 241, 158 - 160

• Reflex muscle contraction in anterior shoulder instability.

  Wallace DA. et al, (1997), J Shoulder Elbow Surg, 6, 150 - 155

• The problem of 'noise' in monitoring patient-based outcomes: generic, disease-specific and site-specific instruments for total hip replacement.

  Dawson J. et al, (1996), J Health Serv Res Policy, 1, 224 - 231

• Familial tendency to severe symptomatic osteoarthritis of the hip and knee.

  Chitnavis J. et al, (1996), ARTHRITIS AND RHEUMATISM, 39, 857 - 857

• Questionnaire on the perceptions of patients about shoulder surgery.

  Dawson J. et al, (1996), J Bone Joint Surg Br, 78, 593 - 600

• Lateral unicompartmental arthroplasty with the Oxford meniscal knee

  Gunther TV. et al, (1996), The Knee, 3, 33 - 39

• Comparison of measures to assess outcomes in total hip replacement surgery.

  Dawson J. et al, (1996), Qual Health Care, 5, 81 - 88

• Questionnaire on the perceptions of patients about total hip replacement.

  Dawson J. et al, (1996), J Bone Joint Surg Br, 78, 185 - 190

• An evaluation of the Constant-Murley shoulder assessment.

  Conboy VB. et al, (1996), J Bone Joint Surg Br, 78, 229 - 232

• Fibrogenesis imperfecta ossium.

  Carr AJ. et al, (1995), J Bone Joint Surg Br, 77, 820 - 829

• Which primary total hip replacement?

  Murray DW. et al, (1995), J Bone Joint Surg Br, 77, 520 - 527

• Chondrocalcinosis and medial unicompartmental knee arthroplasty

  Woods DA. et al, (1995), The Knee, 2, 117 - 119

• Aetiological factors in severe osteoarthritis of the knee

  Wallace DA. et al, (1995), The Knee, 2, 113 - 115

• Differential allelic expression of the type II collagen gene (COL2A1) in osteoarthritic cartilage.

  Loughlin J. et al, (1995), Am J Hum Genet, 56, 1186 - 1193

• Pharmacological thromboprophylaxis and total hip replacement.

  Murray DW. et al, (1995), J Bone Joint Surg Br, 77, 3 - 5

• Septic arthritis of the shoulder presenting as chronic anterior dislocation.

  Wallace DA. and Carr AJ., (1994), J Shoulder Elbow Surg, 3, 402 - 403

• Day case arthroscopy under local anaesthesia.

  Wallace DA. et al, (1994), Ann R Coll Surg Engl, 76, 330 - 331

• SURVIVAL ANALYSIS - AUTHORS REPLY

  MURRAY D. et al, (1994), JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 76B, 508 - 508

• The management of isolated distal radius fractures in children.

  Gibbons CL. et al, (1994), J Pediatr Orthop, 14, 207 - 210

• Medial unicompartmental arthroplasty. A survival study of the Oxford meniscal knee.

  Carr A. et al, (1993), Clin Orthop Relat Res, 205 - 213

• Survival analysis of joint replacements.

  Murray DW. et al, (1993), J Bone Joint Surg Br, 75, 697 - 704

• ANTEVERSION IN CONGENITAL DISLOCATION OF THE HIP - REPLY

  BENSON M. and CARR A., (1993), JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 75, 837 - 837

• The Oxford knee. Survival analysis of joint replacement.

  Carr AJ., (1993), Int Orthop, 17, 14 - 15

• Rupture of the ulnar collateral ligament of the thumb in a 5-year-old girl.

  Wallace DA. and Carr AJ., (1993), J Hand Surg Br, 18

• Designer hips.

  Bulstrode CJ. et al, (1993), BMJ, 306, 732 - 733

• Survival analysis in joint replacement surgery.

  Carr AJ. et al, (1993), J Bone Joint Surg Br, 75, 178 - 182

• Joint laxity and hip rotation in normal children and in those with congenital dislocation of the hip.

  Carr AJ. et al, (1993), J Bone Joint Surg Br, 75, 76 - 78

• Family stature in idiopathic scoliosis.

  Carr AJ. et al, (1993), Spine (Phila Pa 1976), 18, 20 - 23

• Rupture of extensor tendons due to osteoarthritis of the distal radio-ulnar joint.

  Carr AJ. and Burge PD., (1992), J Hand Surg Br, 17, 694 - 696

• The radiographic classification of medial gonarthrosis. Correlation with operation methods in 200 knees.

  Keyes GW. et al, (1992), Acta Orthop Scand, 63, 497 - 501

• Segregation of structural collagen genes in adolescent idiopathic scoliosis.

  Carr AJ. et al, (1992), Clin Orthop Relat Res, 305 - 310

• JOY RIDING

  GIBBONS C. et al, (1991), BRITISH MEDICAL JOURNAL, 303, 650 - 650

• An analysis of normal back shape measured by ISIS scanning.

  Carr AJ. et al, (1991), Spine (Phila Pa 1976), 16, 656 - 659

• Familial back shape in adolescent scoliosis. A photogrammetric population study.

  Carr AJ. et al, (1991), Acta Orthop Scand, 62, 131 - 135

• Avoidable causes of cancellation in elective orthopaedic surgery.

  Wildner M. et al, (1991), Health Trends, 23, 115 - 116

• Adolescent idiopathic scoliosis in identical twins.

  Carr AJ., (1990), J Bone Joint Surg Br, 72

• THORACIC KYPHOSIS MEASUREMENTS FROM ISIS SCANS

  JEFFERSON R. et al, (1990), SURFACE TOPOGRAPHY AND BODY DEFORMITY, 61 - 63

• Idiopathic thoracic kyphosis in identical twins.

  Carr AJ., (1990), J Bone Joint Surg Br, 72

• CORRECTION OF BODY HEIGHT IN SCOLIOTIC PATIENTS USING ISIS SCANNING

  CARR A. et al, (1990), SURFACE TOPOGRAPHY AND BODY DEFORMITY, 65 - 67

• Surface stereophotogrammetry of thoracic kyphosis.

  Carr AJ. et al, (1989), Acta Orthop Scand, 60, 177 - 180

• Back shape in brace treatment of idiopathic scoliosis.

  Weisz I. et al, (1989), Clin Orthop Relat Res, 157 - 163

• Correction of body height in scoliotic patients using ISIS scanning.

  Carr AJ. et al, (1989), Spine (Phila Pa 1976), 14, 220 - 222

• The blood supply of the calcaneal tendon.

  Carr AJ. and Norris SH., (1989), J Bone Joint Surg Br, 71, 100 - 101

• The blood supply of the osteocutaneous free fibular graft.

  Carr AJ. et al, (1988), J Bone Joint Surg Br, 70, 319 - 321

• RADIOLOGY OF FISH BONE FOREIGN-BODIES IN THE NECK

  CARR A., (1987), JOURNAL OF LARYNGOLOGY AND OTOLOGY, 101, 407 - 408

• Costs, quality of life and cost-effectiveness of open and arthroscopic repair for rotator cuff tears: economic evaluation alongside the UKUFF trial

  Murphy JFE. et al, Bone and Joint Journal

• Comparison of TGFβ expression in healthy and diseased human tendon

  Dakin SG. et al, Arthritis Research and Therapy

Key Publications

• Arthroscopic surgery for degenerative knee.

  Carr A., (2015), BMJ, 350

• Fabrication of continuous electrospun filaments with potential for use as medical fibres.

  Mouthuy PA. et al, (2015), Biofabrication, 7
• Preclinical target validation using patient-derived cells.

  Edwards AM. et al, (2015), Nat Rev Drug Discov, 14, 149 - 150
• Changing the mindset in life sciences toward translation: a consensus.

  Duda GN. et al, (2014), Sci Transl Med, 6
• Advances in arthroscopy-indications and therapeutic applications.

  Carr AJ. et al, (2015), Nat Rev Rheumatol, 11, 77 - 85
• Use of placebo controls in the evaluation of surgery: systematic review.

  Wartolowska K. et al, (2014), BMJ, 348

• Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England: retrospective cohort analysis of hospital episode statistics.

  Kendal AR. et al, (2013), BMJ, 347

• Understanding of regional variation in the use of surgery.

  Birkmeyer JD. et al, (2013), Lancet, 382, 1121 - 1129
• Knee replacement.

  Carr AJ. et al, (2012), Lancet, 379, 1331 - 1340

Recent Publications

• Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

  Quek L. et al, (2016), J Exp Med, 213, 1513 - 1535
• A comparative evaluation of the effect of polymer chemistry and fiber orientation on mesenchymal stem cell differentiation.

  Rowland DC. et al, (2016), J Biomed Mater Res A
• Surrogate markers of long-term outcome in primary total hip arthroplasty: A systematic review.

  Malak TT. et al, (2016), Bone Joint Res, 5, 206 - 214
• Maternal gestational vitamin D supplementation and offspring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial.

  Cooper C. et al, (2016), Lancet Diabetes Endocrinol, 4, 393 - 402
• Dickkopf-3 is upregulated in osteoarthritis and has a chondroprotective role.

  Snelling SJ. et al, (2016), Osteoarthritis Cartilage, 24, 883 - 891