Loretta Davies

SITU Trials Portfolio Manager (Operational Lead)

I joined the NDORMS department in January 2010 as the TOPKAT Trial Coordinator, a multi-centre NIHR HTA funded study which aims to assess the clinical and cost effectiveness of total or partial knee replacements in patients with medial compartment osteoarthritis.

Prior to this I worked as a physiotherapist with particular interest orthopaedics and exercise rehabilitation in chronic disease and completed an MSc in Applied Sport and Exercise Physiology in 2009.

I am currently studying for a DPhil in Musculoskeletal Sciences at the University of Oxford with a focus on the challenges in the design and conduct of surgical trials

Recent publications

Comparison of the clinical and cost effectiveness of two management strategies (rehabilitation versus surgical reconstruction) for non-acute anterior cruciate ligament (ACL) injury: study protocol for the ACL SNNAP randomised controlled trial.
Journal article

Davies L. et al, (2020), Trials, 21
Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT.
Journal article

Beard DJ. et al, (2020), Health technol assess, 24, 1 - 98
The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial.
Journal article

Beard DJ. et al, (2019), Lancet, 394, 746 - 756
Evidence-Based Evaluation of Practice and Innovation in Physical Therapy Using the IDEAL-Physio Framework.
Journal article

Beard D. et al, (2018), Phys ther, 98, 108 - 121
Surgical versus conservative interventions for treating anterior cruciate ligament injuries.
Journal article

Monk AP. et al, (2016), Cochrane database syst rev, 4

More publications