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A new method of treating wounds after major trauma costing nearly £150 per dressing is no more effective in reducing surgical infection rates than a standard wound dressing priced under £2, potentially saving the NHS millions.

Op-site dressing at laparotomy wound applied immediately to the patient after surgery. © Shutterstock

New guidelines to build trusted AI in healthcare research

A new set of guidelines have been launched to create trustworthy AI systems in healthcare. The first of its kind, the FUTURE-AI guideline provides recommendations covering the entire lifecycle of medical AI, from design, development and validation to regulation, deployment, and monitoring.

New theory explains reporting of suspected adverse drug reactions to biological therapies used in rheumatology care

A recent study introduces "Pragmatic Situational Practice Outcomes," shedding light on the complexities affecting how patients and healthcare professionals report suspected ADRs related to biologic medications.

Stephanie Dakin awarded a Versus Arthritis Bridging Fellowship

Professor Stephanie Dakin has been awarded a Versus Arthritis Bridging Fellowship to advance the work of her Versus Arthritis sponsored Career Development Fellowship investigating frozen shoulder.

Laura Coates becomes the first rheumatologist to receive prestigious NIHR professorship

The first ever rheumatologist to be awarded an NIHR Research Professorship, Laura will use the funding to further her research into psoriasis and psoriatic arthritis aiming to transform patient care and treatment personalisation.

James Fullerton awarded a British Pharmacological Society Fellowship

Associate Professor James Fullerton has been awarded Fellowship of the British Pharmacological Society (BPS) following a recommendation by their Honors and Fellows Panel, recognising his sustained contribution to the discipline of Clinical Pharmacology and Therapeutics.

Machine learning outperforms surgeons in predicting knee replacement outcomes

A new study has revealed that machine learning models can significantly outperform experienced surgeons in predicting patient outcomes after partial knee replacement.

NDORMS study highlights lingering symptoms long after COVID-19 infection

A new international study has shed light on the significant burden of post-acute COVID-19 symptoms across N. America, Europe and Asia.

Oxford space lab experiment heads to International Space Station

The first human tissue samples from Oxford's Space Innovation Lab (SIL) have been launched and are on their way to the International Space Station, where they will be used to study the effects of space microgravity on the human ageing process.

Post-acute infection syndrome is not unique to COVID-19

Patients hospitalised with COVID-19 often report a wide range of symptoms months after their initial illness. But a new study from NDORMS shows that post-acute infection syndrome (PAIS) is not unique to COVID-19 and can also occur after other respiratory infections.

NDORMS joins the Human Functional Genomics Initiative

£28.5m in funding has been announced to support functional genomics research across the UK, including a research cluster at NDORMS that will deliver insights into musculoskeletal health and disease.

Healthy lifestyle lowers the risk of post-COVID complications

A new NDORMS study has found that a healthy lifestyle can significantly reduce the risk of post-COVID complications, hospitalisation, and death.

New prediction model could help inform patients of their risks of having shoulder replacement surgery

A new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between researchers from the University of Oxford, University of Bristol, and University of Copenhagen. The model could be an important tool to help both patients and doctors make more informed decisions about this common procedure.

NDORMS tests AI algorithms for medical diagnoses

NDORMS has joined RAIQC as one of eight other NHS, industry and academic consortium partners in Trustworthy AI Evaluation.

New PI will study human iron metabolism, kinetics and physiology in health and inflammatory disease

We welcome Nicole Stoffel who has joined the Botnar Institute as a new Principal Investigator. Nicole will be establishing her group to better understand human iron metabolism, kinetics and physiology with a specific focus on the role iron plays in the immune response and the impact of iron deficiency on vaccine effectiveness.

Uncovering the cellular secrets of healthy tendons

Research has unveiled the intricate cellular landscape of healthy human hamstring tendons, shedding new light on this vital yet often overlooked component of our musculoskeletal system.

New real-world evidence network co-ordination centre for the UK

Daniel Prieto-Alhambra from NDORMS is to lead a new co-ordination centre for a pilot real-world evidence network to utilise data gathered from multiple UK sources.

Study uncovers how cancer stem cells spread and resist treatment

NDORMS researchers have identified a critical axis that controls the formation and behaviour of cancer stem cells (CSCs), a subpopulation of cells that influence how lethal the cancer can be, its resistance to chemotherapy, and its ability to spread to other parts of the body.

New therapeutic avenues in bone repair

An ongoing research collaboration between NDORMS and University of Birmingham researchers has shown that PEPITEM, a naturally occurring peptide (small protein), holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct advantages over existing drugs.

Cracking the genetic code for COVID-19 vaccine effectiveness

Researchers have unveiled critical insights into how our genetic makeup influences the body's response to COVID-19 vaccines. The study, published in Nature Communications, may open new paths to personalised vaccination strategies.

New Maternity Early Warning Score to be implemented across the NHS

Researchers in Oxford have developed a new maternity early warning score that is derived from patient data. The new system, which is being rolled out across the English NHS, will help healthcare providers identify and respond to signs of deterioration in pregnant women.

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Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound Dressing on Deep Surgical Site Infection After Surgery for Lower Limb Fractures Associated With Major Trauma

JAMA

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