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New research from a randomised clinical trial published today in The Lancet and funded by the National Institute for Health Research (NIHR) shows that partial knee replacements (PKR) are as good as total knee replacements (TKR), whilst being more cost effective.
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Dakin Group | Soft Tissue Joint Disease
The Dakin Group undertakes translational research focusing on identifying the cellular and molecular basis of inflammatory fibrotic soft tissue joint diseases, with research programmes on tendinopathy, frozen shoulder and knee arthrofibrosis. Understanding the cellular and molecular basis of these diseases will inform new therapeutic approaches targeting tissue resident stromal cells of the joint, to promote resolution of inflammatory fibrotic disease.
Hulley Group | Integrated musculoskeletal tissue modelling
Hulley group research is directed towards understanding skeletal tissue disease pathology and devising effective regenerative strategies.
Meet the NDORMS team
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David Beard
Professor of Musculoskeletal and Surgical Science
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Loretta Davies
SITU Trials Portfolio Manager (Operational Lead)
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Jonathan Cook
Professor of Clinical Trials & Medical Statistics/OCTRU Deputy Director
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Andrew Price
Professor of Orthopaedics Surgery
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Andrew Carr
Nuffield Professor of Orthopaedics
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David Murray
Professor of Orthopaedic Surgery
Read the paper
The clinical and cost effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised trial.
The Lancet 2019.
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