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Published in The Lancet Oncology journal, the 10-patient phase 1 clinical trial used focussed ultrasound from outside the body to selectively heat liver tumours and trigger drug release from heat-sensitive carriers, known as thermosensitive liposomes. Building on over a decade of preclinical studies, the study demonstrated the ultrasound technique to be feasible, safe, and capable of increasing drug delivery to the tumour between two-fold and ten-fold in the majority of patients.
Maria Sanchez Santos
Botnar CSM Research Scientists
BSc, MSc Maria Sanchez Santos - Senior Research Associate in Epidemiology and Medical Statistic
Adrian Kendal
Honorary staff
MA (Oxon.) BMBCh, DPhil (Oxon.), FRCS (Ortho.) Adrian Kendal - Honorary Senior Clinical Lecturer
Vicki Barber
Botnar CSM OCTRU Research Delivery Research Scientists
BSc (Hons) ; FIoB; PhD Vicki Barber - OCTRU Operations Director
Philippa Hulley
Botnar Principal Investigators
BSc Med, BSc Med (Hons), PhD Philippa Hulley - Associate Professor
Antonella Delmestri
Botnar CSM Research Scientists
PhD Antonella Delmestri - Lead Health Data Scientist
Srinivasa Rao Rao
Research Scientists
MBBS, MS (res), DPhil, AFHEA Srinivasa Rao Rao - Principal Investigator
Gary Collins
CSM Principal Investigators
PhD Gary Collins - Professor of Medical Statistics and Director of CSM
Karene Argoud
Kennedy Research Scientists
Karene Argoud - Single-Cell and Spatial Genomics Operations Technician
Dave Banfield
Botnar Facilities Professional Services
Dave Banfield - Buildings and Facilities Manager
Siim Pauklin
Botnar Principal Investigators
Siim Pauklin - Associate Professor and CRUK Career Development Fellow
Andrew Carr
OCTRU Principal Investigators
MA ChM DSc FRCS FMedSci Andrew Carr - Nuffield Professor of Orthopaedics
Katie Chegwin
Botnar Professional Services SITU
Katie Chegwin - Personal Assistant to Professor David Beard
Hanna Boddy
Kennedy Professional Services
Hanna Boddy - Executive Assistant to the Director of the Kennedy Institute
Ivy Raymundo Wood
Research Delivery SITU
BSc (Hons) Ivy Raymundo Wood - Senior Clinical Trial Manager
Veronika Pfannenstil
Kennedy Research Scientists
Veronika Pfannenstil - Postdoctoral Research Assistant