American Association Orthopaedic Surgeons Conference 2025 Best in Class Prize Winner

Chang Chen Award, British Orthopaedic Foot Ankle Society 2025

The European Federation of National Associations of Orthopaedics and Traumatology Bronze Medal Award 2025

The Presidential Prize, European Society for Foot and Ankle Surgery 2025 

British Othopaedic Foot Ankle Society

Royal College Surgeons

European Foot Ankle Society

BoneSupport

Adrian's research aim is to improve the care of patients with lower limb musculoskeletal disease. He uses big data analytical techniques to understand musculoskeletal pathology at a cellular level as well as the outcomes of surgical intervention at a national population level.

Adrian aims to understand the pathogenesis of chronic debilitating tendon disease. Tendinopathy accounts for over 20% of primary care consultations and represents a growing healthcare challenge in an active and increasingly ageing population. Recognising critical cells involved in tendinopathy is essential in developing therapeutics to meet this challenge. Adrian has applied combined single cell transcriptomics and surface proteomics to identify novel tendon cell sub-types in diseased and healthy human tendon. For the first time, he showed that human tendon harbours multiple distinct COL1A1/2 expressing tenocyte populations in addition to endothelial cells, T-cells, and monocytes. Adrian is interested in the temporal-spatial interaction of particular tendon cell sub-types in the pathogenesis of chronic tendinopathy, for example pro-inflammatory PTX3 cells and signalling pathways.

At a national population level, Adrian has led England population based studies that define the long-term safety, durability, and complication profiles of common foot and ankle procedures. It defines benchmarks for the delivery of high-volume operations—such as hallux valgus surgery—providing evidence to support counselling, equitable access, service delivery, and quality improvement across the NHS. He has compared treatment pathways for end-stage ankle arthritis, generating real-world revision trajectories that inform shared decision-making when choosing between total ankle replacement and ankle fusion. His population based analysis on below-knee amputation in people with diabetes emphasises the unacceptably high rate of  post-operative mortality, re-intervention, and readmission in this vulnerable patient group.