Adrian Kendal
MA (Oxon.) BMBCh, DPhil (Oxon.), FRCS (Ortho.)
Honorary Departmental Clinical Research Associate
- Honorary Clinical Research Associate
- Specialist Orthopaedic Surgeon with subspecialty interest in Foot and Ankle Reconstruction
- Lecturer at Trinity College, Oxford
Adrian's research aim is to understand the pathogenesis of chronic debilitating tendon disease. Tendon disease accounts for over 20% of primary care consultations and represents a growing healthcare challenge in an active and increasingly ageing population. Recognising critical cells involved in tendinopathy is essential in developing therapeutics to meet this challenge.
Adrian has applied combined single cell transcriptomics and surface proteomics to identify novel tendon cell sub-types in diseased and healthy human tendon. For the first time, he has shown that human tendon harbours multiple distinct COL1A1/2 expressing tenocyte populations in addition to endothelial cells, T-cells, and monocytes. Adrian is interested in the temporal-spatial interaction of particular tendon cell sub-types in the pathogenesis of chronic tendinopathy, for example pro-inflammatory PTX3 cells and signalling pathways.
Recent publications
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Association of Preexisting Triple Fusion and Arthroscopic Ankle Arthrodesis nonunion.
Journal article
Woods A. et al, (2023), Foot ankle int
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Long-Term Follow-up of Complex Calcaneal Osteomyelitis Treated With Modified Gaenslen Approach.
Journal article
Kendal A. et al, (2022), Foot ankle orthop, 7
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The Application and Patient-Reported Experience of Telephone Consultations in Elective Foot and Ankle Orthopaedic Surgery: 12-Month Follow-up.
Journal article
Sharma A. et al, (2022), Foot ankle int, 43, 694 - 702
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Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon.
Journal article
Kendal AR. et al, (2020), Sci rep, 10
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Identification of human tendon cell populations in healthy and diseased tissue using combined single cell transcriptomics and proteomics
Journal article
Kendal AR. et al, (2019)
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Conversion rate of isolated talo-calcaneal (subtalar) arthrodesis to triple fusion; five year study
Journal article
(2018), Foot and ankle surgery
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Resorbable electrospun polydioxanone fibres modify the behaviour of cells from both healthy and diseased human tendons.
Journal article
Kendal A. et al, (2017), Eur cell mater, 33, 169 - 182
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Fracture healing in the elderly: A review.
Journal article
Foulke BA. et al, (2016), Maturitas, 92, 49 - 55
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Mortality rates at 10 years after metal-on-metal hip resurfacing compared with total hip replacement in England.
Journal article
Kendal AR. et al, (2016), Br j sports med, 50
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Induced Foxp3(+) T Cells Colonizing Tolerated Allografts Exhibit the Hypomethylation Pattern Typical of Mature Regulatory T Cells.
Journal article
Hilbrands R. et al, (2016), Front immunol, 7
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Complications of minimally invasive calcaneal osteotomy versus open osteotomy.
Journal article
Kendal AR. et al, (2015), Foot ankle int, 36, 685 - 690
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Arthroscopic Ankle Fusion for Avascular Necrosis of the Talus
Journal article
Kendal AR. et al, (2015), Foot & ankle international, 36, 591 - 597