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Published in The Lancet Oncology journal, the 10-patient phase 1 clinical trial used focussed ultrasound from outside the body to selectively heat liver tumours and trigger drug release from heat-sensitive carriers, known as thermosensitive liposomes. Building on over a decade of preclinical studies, the study demonstrated the ultrasound technique to be feasible, safe, and capable of increasing drug delivery to the tumour between two-fold and ten-fold in the majority of patients.
Vicki Barber
Botnar CSM OCTRU Research Delivery Research Scientists
BSc (Hons) ; FIoB; PhD Vicki Barber - OCTRU Operations Director
Andrew Carr
OCTRU Principal Investigators
MA ChM DSc FRCS FMedSci Andrew Carr - Nuffield Professor of Orthopaedics
Joanna Black
Botnar CSM OCTRU Research Delivery
BSc, PhD Joanna Black - OCTRU Head of Regulatory Affairs and Quality Assurance (HoRAQ)
Anne Francis
Botnar OCTRU Research Scientists
D.Phil Anne Francis - Clinical Trial Operational Lead – Experimental Medicine and Rheumatology
Emma Phelps
Botnar Kadoorie OCTRU Research Scientists
Emma Phelps - Postdoctoral Research Associate in Mixed Methods Research
Esther Williamson
Botnar OCTRU Research Scientists
Esther Williamson - Deputy Director, Centre for Rehabilitation Research in Oxford
Susan Wagland
Botnar Kadoorie OCTRU Research Delivery
BA, BSc, MSc, PhD Susan Wagland - Clinical Trials Manager
Emma Haines
Botnar CSM OCTRU Research Delivery
Emma Haines - OCTRU - Quality Assurance and Administration Manager