Search results
Found 351 matches for
No link found between patient genetics and response to anti-IL17 therapy
4 September 2023
A new study looked at the effect of patient genetics on their response to secukinumab, an anti-IL17 therapy commonly used to treat inflammatory conditions including arthritis and psoriasis. No link was found between a patient’s genetic variants and their response to therapy. This study challenges the idea that genetics might significantly account for the variable responses to anti-IL17 therapy seen in the clinic.
Building a humanoid bioreactor
8 June 2022
A humanoid robot is being used at NDORMS in an attempt to grow tendon tissue for repairing shoulder injuries.
REF 2021 results for medical research in Oxford
12 May 2022
Today the UK Funding Bodies have published the outcomes of the recent national research assessment exercise, the Research Excellence Framework (REF) 2021.
Liposomal bupivacaine found to be no more effective than current treatments for post-operative knee pain
6 April 2022
A new study published in JAMA, has found that a drug recently licensed in the UK has no effect on post-operative knee replacement recovery or pain, compared to the current treatment when administered at site of surgery.
New research suggests targeting blood vessels could be key to controlling fibrotic disease
1 April 2022
By studying blood vessels at single cell resolution, Professor Jagdeep Nanchahal and colleagues found that in Dupuytren’s disease, a fibrotic disorder of the hand, the vasculature is key to orchestrating the development of human fibrosis.
AI helps to detect bone fractures to 92% accuracy
31 March 2022
Research from the Botnar Institute for Musculoskeletal Sciences shows that Artificial intelligence (AI) is an effective tool for fracture detection that has potential to aid clinicians in busy emergency departments.
Defining the role of resident memory B cells in the fight against influenza
31 March 2022
Researchers at the Kennedy Institute of Rheumatology have used 3D and live-imaging to show how resident memory B cells boost antibodies to fight influenza.
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
23 March 2022
The COVID-19 Multi-omic Blood Atlas (COMBAT) has identified blood hallmarks of COVID-19 involving particular immune cell populations and their development, components of innate and adaptive immunity, and connectivity with the inflammatory response.
Funding boost for early-stage clinical research
8 March 2022
Oxford is one of 28 sites that will benefit from over £160 million awarded over five years to expand early phase clinical research for the benefit of NHS patients.
Arm and shoulder disability and pain after breast cancer surgery reduced by exercise
15 November 2021
The debilitating arm and shoulder disability and pain that some women who have had breast cancer surgery experience as a side effect of their surgery can be reduced by following a physiotherapy-led exercise programme after their operation, a new study has found.
New therapeutic targets identified to treat inflammatory bowel disease
22 October 2021
Millions of patients with ulcerative colitis or Crohn’s disease, collectively known as inflammatory bowel disease (IBD), are given fresh hope as a new study shows why some of them do not respond to current treatments.
New guidelines to improve reporting standards of studies that investigate causal mechanisms
21 September 2021
Researchers at NDORMS have developed a new set of guidelines for reporting mediation analyses in health research.
NDORMS researchers awarded grant for study on the effects of COVID-19 vaccines on long COVID
19 July 2021
A team of NDORMS researchers including Doctor Annika Jödicke and Doctor Victoria Strauss have been awarded NIHR funding to carry out a study into the effects of different COVID-19 vaccines on long COVID.
Exploring the link between joint injury and osteoarthritis
25 June 2021
A new study published in The Lancet Rheumatology shows potential ways to predict how likely someone is to develop osteoarthritis after a knee injury.
Research finds that surgery for Dupuytren’s disease is effective, but repeat operations come with higher risks
4 June 2021
Research by NDORMS Dominic Furniss, Professor of Plastic and Reconstructive Surgery, finds that surgery for the common hand disorder Dupuytren’s disease is safe and effective. However, repeat surgery could carry higher risks of complications such as finger amputation.
Celebrating World Clubfoot Day
3 June 2021
More than 30,000 children in Africa are born with clubfoot each year. With treatment simply not available where they live, many thousands of these children get no treatment and end up with severe deformities that make it hard and very painful to walk.
Repurposed drug can induce remission of inflammatory arthritis
20 May 2021
Researchers at the Kennedy Institute demonstrate that the drug decitabine can boost regulatory T cell responses.
Study reveals the three most important aspects of care for hip fractures
5 May 2021
Older patients with hip fractures recover better if they receive treatment under the supervision of both a surgeon and a specialist in elderly care; are checked to avoid future falls; and are assessed for memory problems.
The role of mAbs (neutralising monoclonal antibodies) in the fight against COVID-19
30 April 2021
Neutralising mAbs, a form of anti-viral medicine, are being explored as an attractive option to treat symptoms of COVID-19 and in some cases prevent infection. But what are the pros and cons of this type of treatment and what should regulators consider before granting approval?