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Maria Kyriazi

MRes | BSc (Hons)


DPhil student

Mellon Longevity Graduate Scholar | Onassis Foundation Scholar

Maria is a third-year DPhil in Molecular and Cellular Medicine under the supervision of Associate Professor Ghada Alsaleh and Professor Lynne Cox. She investigates the age-related mechanisms that drive progressive tissue damage, with a primary focus on the joints. The aim of her research is to elucidate the underlying pathways that deteriorate with advanced age, which may contribute to the development of osteoarthritis.

Before pursuing her DPhil, Maria completed her Bachelor's degree in Biomedical Genetics at Newcastle University. During that time, she investigated changes in oocyte meiosis associated with female chromosomal ageing under the supervision of Professor Mary Herbert. 

After the completion of her undergraduate studies, she obtained a Master of Research (MRes) in Ageing and Health through a collaboration between Newcastle University and the University of Oxford. During her MRes, she explored the role of autophagy in osteoarthritis supervised by Associate Professor Ghada Alsaleh and Dr Sarah Rice.

Currently, her DPhil project delves into the molecular and mechanistic age-related changes that deteriorate the joints and lead to musculoskeletal diseases. Overall, her research aims to identify the biological changes that develop with advanced biological age and predispose older adults to develop musculoskeletal disease.