Early versus delayed weight-bearing following operatively treated ankle fracture (WAX): a non-inferiority, multicentre, randomised controlled trial
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Welcome to Oxford Trauma and Emergency Care
Trauma and emergencies are huge issues for patients, the NHS and society more broadly. Oxford Trauma and Emergency Care seeks to improve patient care by designing and testing new treatments and new treatment pathways. We aim to deliver better outcomes for patients and more efficient care within the NHS and other healthcare system worldwide.
We run a number of clinical trials and related studies in trauma and emergency care to guide best practice in the field. Our work informs practice and policy in the NHS and internationally through bodies such as the National Institute for Health and Care Excellence (NICE) guidelines.
Oxford Trauma and Emergency Care is based in the Kadoorie Centre located at the John Radcliffe Hospital, but has collaborations across the University and outside.
Our research focuses on the clinical and cost effectiveness of orthopaedic surgery.
August 2025 TRIAL STATS
Participants recruited
317
Sites with the most recruits in July
John Radcliffe Hospital with 24
New sites open in July
Heartlands Hospital Birmingham (WHiTE 14 'PRESSURE 3')
Whipps Cross University Hospital (WHiTE 13 'DECI')
Derriford Hospital, Norfolk and Norwich University Hospital, and Great Ormond Street Hospital (Op Non-STOP)
Darent Valley Hospital (WHiTE 15 'INITIATE')
The Royal Belfast Hospital for Sick Children (ODDSOCKS)
Work with us
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Clinical Trial Manager (181983)
Closing date: 26 September 2025
Are you organised, enthusiastic, and have experience in running clinical trials? You could be the Kadoorie's new Clinical Trial Manager!
TEAM
RESEARCH
EVENTS
Latest news
Associate Professor reaches new heights with the Thames Valley Air Ambulance
23 June 2025
David Metcalfe, Associate Professor of Emergency Medicine at NDORMS, has begun a two-year secondment with Thames Valley Air Ambulance.
David Keene appointed to Kadoorie Professorship of Trauma Rehabilitation
2 June 2025
David Keene will lead advanced research and teaching in trauma rehabilitation at Oxford Trauma and Emergency Care within NDORMS.
New donation secures future of Emergency Medicine research at Oxford
7 August 2024
A new research programme in emergency medicine begins today at the University of Oxford following a donation from the Kadoorie Foundation.
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