Contact information
Research groups
Alex Clarke
PhD FRCP
Associate Professor and Honorary Consultant Rheumatologist, Nuffield Orthopaedic Centre
- Associate Professor
- Honorary Consultant Rheumatologist, Nuffield Orthopaedic Centre
I qualified in Medicine from UCL in 2001, and trained in Rheumatology in London. Supported by a Wellcome Trust Clinical Research Training Fellowship, I completed a PhD on the role of autophagy in lupus in 2013, supervised by Tim Vyse at King’s College London.
After completing my medical specialist training, I moved to Oxford to join the group of Katja Simon at the Weatherall Institute of Molecular Medicine as a postdoctoral clinical fellow in 2014, again supported by the Wellcome Trust.
In 2018 I was awarded a Wellcome Trust Clinical Research Career Development Fellowship, establishing my own group here at the Kennedy Institute of Rheumatology.
Recent publications
The adaptor protein TASL is required for age-related B cell emergence and lupus-like disease development in mice.
Journal article
Johnstone JC. et al, (2026), PLoS Biol, 24
Checkpoint blockade amplifies pro-regenerative type 2 immunity in tissue repair.
Journal article
Romero Arocha S. and Clarke A., (2026), Nat Rev Immunol
Underlying data for 'The adaptor protein TASL is required for age-related B cell emergence and lupus-like disease development in mice'
Dataset
Clarke ALEXANDER., (2026)
Successful treatment of refractory chilblain lupus erythematosus with bosentan.
Journal article
Gunawardana S. et al, (2025), Rheumatology (Oxford), 64, 6430 - 6431
Glycogen synthase kinase-3 is essential for Treg development and function.
Journal article
Kandasamy M. et al, (2025), Cell Rep, 44