Research groups
Lei Clifton
BSc, MSc, PhD
Honorary Departmental Senior Medical Statistician
Statistical expertise in epidemiology and clinical studies.
I joined the Nuffield Department of Population Health (NDPH) in 2019 as the team leader of the Translational Epidemiology Unit (TEU), under its Director Prof David Hunter. I lead a programme of research in translational cancer epidemiology. Key research includes assessing the performance of large-scale information on lifestyle and environment, assisting in development of exposure assessment instruments suitable for use at scale.
From 2014 - 2018, I worked in the Centre for Statistics in Medicine (CSM), where I lead statistical work on clinical trials, observational studies, and research on trial methodology. I was a senior advisor on the NIHR Research Design Service (RDS) team, which provides free advice on research design to researchers in the South Central region. I collaborated extensively with principle investigators in trial design and grant applications.
During my 5 years in CSM, I also provided statistical supervision in fellowship applications, taught statistics at the postgraduate level, and review grant proposals for the NIHR. I was a Scientific Research Committee (SRC) member of the Northern Ireland Chest Heart and Stroke (NICHS), responsible for reviewing proposals and allocating research grants.
From 2009 - 2014, I worked in the Institute of Biomedical Engineering, in the University of Oxford, where I undertook research into statistical time-series models for providing early warning of deterioration in post-surgery patients. From 2007-2009, I was a post-doctoral researcher in the Nuffield Department of Clinical Neurosciences, University of Oxford, where I developed mathematical models and prototype apparatus for measuring the lung function of ICU patients.
I was awarded a PhD in Statistical Signal Processing in 2007 from UMIST (now the University of Manchester), after completing my BSc and MSc degrees in Electrical Engineering at the Beijing Institute of Technology, China. I joined CSM in 2014.
Joining CSM and then NDPH has been one of the best choices I have made in my life, as I thoroughly enjoy working with the team on epidemiology and other medical studies. When I am at home, you can find me practising yoga, making noise on the violin, planting in the garden, or sewing pillowcases for my two boys.
Recent publications
Assessing the Importance of Variation in Diagnostic Coding Among the Three Countries in the UK Biobank.
Journal article
Clifton L. et al, (2026), Learn Health Syst, 10
Early plasma proteomic alterations precede amyloidosis diagnosis, reflecting cardiac and immune dysregulation
Preprint
Hasheminasab SA. et al, (2026)
Digital morphine: why AI scribes are symptomatic relief for a broken system
Journal article
Segal B. et al, (2026), BMJ Digital Health & AI, 2, e000030 - e000030
Democratising Clinical AI through Dataset Condensation for Classical Clinical Models
Preprint
Thakur A. et al, (2026)