Contact information

Benjamin Speich

Postdoctoral Research Fellow

I joined NDORMS in 2018 and will be working in the Centre for Statistics in Medicine for a 2-year postdoctoral fellowship funded by the Swiss National Science Foundation. My work is in the area of Research on Research, focusing on “Improving the reporting in randomised trials through observational and interventional research: from study protocols and registries to full text publications”.

I did my PhD at the Swiss Tropical and Public Health Institute in Basel between 2011 and 2014. During my PhD I assessed different treatment options for intestinal helminth infections in a number of randomised controlled trials conducted in Tanzania.

After that I worked as a research fellow in the surgical department of the Kantonal Hospital Baselland and as a Postdoctoral researcher and clinical consultant at the University Hospital Basel. During that time, I conducted research on research, systematic reviews and worked in on several randomised clinical trials as a consultant.

Key publications

Systematic review on costs and resource use of randomized clinical trials shows a lack of transparent and comprehensive data.
Journal article

Speich B. et al, (2018), J clin epidemiol, 96, 1 - 11
Effect of sanitation on soil-transmitted helminth infection: systematic review and meta-analysis.
Journal article

Ziegelbauer K. et al, (2012), Plos med, 9
Oxantel pamoate-albendazole for Trichuris trichiura infection.
Journal article

Speich B. et al, (2014), N engl j med, 370, 610 - 620

Recent publications

Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis.
Journal article

Speich B. et al, (2022), Plos med, 19
A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®
Journal article

Speich B. et al, (2021), Trials, 22
Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: a repeated cross-sectional study.
Journal article

Lohner S. et al, (2021), J clin epidemiol
A meta-research study revealed several challenges in obtaining placebos for investigator-initiated drug trials.
Journal article

Speich B. et al, (2021), J clin epidemiol, 131, 70 - 78
One mean to rule them all? The arithmetic mean based egg reduction rate can be misleading when estimating anthelminthic drug efficacy in clinical trials.
Journal article

Moser W. et al, (2020), Plos negl trop dis, 14

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