Claudia Monaco

• Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

  Journal article

  Seneviratne AN. et al, (2017), Circulation, 136, 1140 - 1154

• Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

  Journal article

  Berbée JFP. et al, (2017), Atherosclerosis, 264, 100 - 107

• Imaging vulnerable plaques by targeting inflammation in atherosclerosis using fluorescent-labeled dual-ligand microparticles of iron oxide and magnetic resonance imaging.

  Journal article

  Chan JMS. et al, (2017), Journal of vascular surgery

• Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques.

  Journal article

  Langley SR. et al, (2017), The Journal of clinical investigation, 127, 1546 - 1560

• Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".

  Journal article

  Weber C. et al, (2016), Thrombosis and haemostasis, 116, 626 - 637

• Anti-TNF Therapy.

  Journal article

  Udalova I. et al, (2016), Microbiology spectrum, 4

• Multi-analyte profiling in human carotid atherosclerosis uncovers pro-inflammatory macrophage programming in plaques.

  Journal article

  Shalhoub J. et al, (2016), Thrombosis and haemostasis, 115, 1064 - 1072

• "Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques" (vol 89B, pg 168, 2015)

  Journal article

  Seneviratne AN. et al, (2016), JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 91, 10 - 10

• Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques.

  Journal article

  Seneviratne AN. et al, (2015), Journal of molecular and cellular cardiology, 89, 168 - 172

• Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development.

  Journal article

  Cole JE. et al, (2015), Proceedings of the National Academy of Sciences of the United States of America, 112, 13033 - 13038

• Novel methodologies for biomarker discovery in atherosclerosis.

  Journal article

  Hoefer IE. et al, (2015), European heart journal, 36, 2635 - 2642

• B regulatory cells are increased in hypercholesterolaemic mice and protect from lesion development via IL-10.

  Journal article

  Strom AC. et al, (2015), Thrombosis and haemostasis, 114, 835 - 847

• Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4.

  Journal article

  Montecucco F. et al, (2015), Thrombosis and haemostasis, 114, 410 - 422

• Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.

  Journal article

  Ross EA. et al, (2015), Journal of immunology (Baltimore, Md. : 1950), 195, 265 - 276

• CROSSTALK BETWEEN CD248 AND PDGFR? REGULATES THE PATHOGENIC ROLE OF SMOOTH MUSCLE CELLS IN ATHEROSCLEROSIS

  Conference paper

  Harrison M. et al, (2015), ATHEROSCLEROSIS, 241, E45 - E45

• ANTI-APOA-1 AUTOANTIBODIES INCREASE MOUSE ATHEROSCLROTIC PLAQUE VULNERABILITY, MYOCARDIAL NECROSIS AND MORTALITY TROUGH TLR2 AND TLR4-MEDIATED PATHWAYS

  Conference paper

  Montecucco F. et al, (2015), ATHEROSCLEROSIS, 241, E27 - E27

• Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice.

  Journal article

  Terrando N. et al, (2015), Molecular Medicine, 20, 667 - 675

• Anti-TNF therapy: past, present and future.

  Journal article

  Monaco C. et al, (2015), International immunology, 27, 55 - 62

• Role of inflammatory cells and toll-like receptors in atherosclerosis.

  Journal article

  Seneviratne AN. and Monaco C., (2015), Current vascular pharmacology, 13, 146 - 160

• Macrophages and dendritic cells: the usual suspects in atherogenesis.

  Journal article

  Kassiteridi C. and Monaco C., (2015), Current drug targets, 16, 373 - 382

• Interleukin-6 and microRNA profiles induced by oral bacteria in human atheroma derived and healthy smooth muscle cells.

  Journal article

  Pessi T. et al, (2015), SpringerPlus, 4

• PROTEOMICS ANALYSIS OF EXTRACELLULAR MATRIX IN MURINE ATHEROSCLEROSIS

  Conference paper

  Skroblin P. et al, (2014), ATHEROSCLEROSIS, 237, E4 - E4

• Biomechanical factors in atherosclerosis: mechanisms and clinical implications.

  Journal article

  Kwak BR. et al, (2014), European heart journal, 35, 3013 - 3020d

• Cardiometabolic and immune factors associated with increased common carotid artery intima-media thickness and cardiovascular disease in patients with systemic lupus erythematosus.

  Journal article

  Ammirati E. et al, (2014), Nutrition, metabolism, and cardiovascular diseases : NMCD, 24, 751 - 759

• Imaging of the vulnerable carotid plaque: biological targeting of inflammation in atherosclerosis using iron oxide particles and MRI.

  Journal article

  Chan JM. et al, (2014), European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 47, 462 - 469

• Danger signals in cardiovascular disease.

  Journal article

  Frantz S. et al, (2014), Mediators of inflammation, 2014

• Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: influence of intraluminal flow.

  Journal article

  Caro CG. et al, (2013), Journal of the Royal Society, Interface, 10

• Toll-like receptors in atherosclerosis: a 'Pandora's box' of advances and controversies.

  Journal article

  Cole JE. et al, (2013), Trends in pharmacological sciences, 34, 629 - 636

• M1 macrophages are an early feature of shear stress modulated vulnerable atherosclerotic plaques

  Conference paper

  Seneviratne AN. et al, (2013), EUROPEAN HEART JOURNAL, 34, 443 - 443

• Toll-like receptors in atherosclerosis.

  Journal article

  Falck-Hansen M. et al, (2013), International journal of molecular sciences, 14, 14008 - 14023

• Biomechanical factors and macrophages in plaque stability.

  Journal article

  Seneviratne A. et al, (2013), Cardiovascular research, 99, 284 - 293

• M1 MACROPHAGES AND IRF5 EXACERBATE ATHEROSCLEROTIC DISEASE

  Conference paper

  Seneviratne A. et al, (2013), HEART, 99, A103 - A103

• Smooth muscle cells in human atherosclerosis: proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease.

  Journal article

  Viiri LE. et al, (2013), Journal of molecular and cellular cardiology, 54, 65 - 72

• MACROPHAGE POLARISATION IN SHEAR STRESS MODULATED ATHEROSCLEROTIC PLAQUE VULNERABILITY

  Conference paper

  Seneviratne AN. et al, (2012), ATHEROSCLEROSIS, 225, E2 - E2

• MACROPHAGE ACTIVATION DURING CHRONIC INFLAMMATION IN ATHEROSCLEROSIS

  Conference paper

  Falck-Hansen MA. et al, (2012), ATHEROSCLEROSIS, 225, E3 - E3

• The role of Toll-like receptor-7 in arterial injury

  Conference paper

  Sivagurunathan B. et al, (2012), JOURNAL OF HUMAN HYPERTENSION, 26, 621 - 622

• Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation.

  Journal article

  Salagianni M. et al, (2012), Circulation, 126, 952 - 962

• Antigen-dependent and antigen-independent pathways modulate CD4+CD28null T-cells during atherosclerosis.

  Journal article

  Ammirati E. et al, (2012), Circulation research, 111, e48 - e49

• Novel role of ADAMTS-5 protein in proteoglycan turnover and lipoprotein retention in atherosclerosis.

  Journal article

  Didangelos A. et al, (2012), The Journal of biological chemistry, 287, 19341 - 19345

• Host pattern recognition receptors (toll-like receptors, RIG-I-like receptors, NOD-like receptors) and atherosclerosis

  Chapter

  Feldmann M. and Monaco C., (2012), Inflammation and Atherosclerosis, 9783709103388, 353 - 383

• Arterial stent-associated intimal hyperplasia and wall hypoxia

  Conference paper

  Caro CG. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S116 - S116

• Proteomic study of atheroma-derived smooth muscle cells reveals signatures of increased oxidative stress and mitochondrial dysfunction

  Conference paper

  Viiri LE. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S31 - S32

• Expression of the regulatory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis

  Conference paper

  Falck-Hansen M. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S19 - S19

• B regulatory cells mediate atheroprotection via IL-10

  Conference paper

  Cross A. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S118 - S119

• Macrophage heterogeneity in shear stress modulated atherosclerotic plaque development

  Conference paper

  Seneviratne AN. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S51 - S51

• The metalloproteinase ADAMTS-5 is present in the vasculature and its expression is related to proteoglycan turnover and lipoprotein retention in atherosclerosis

  Conference paper

  Didangelos A. et al, (2012), CARDIOVASCULAR RESEARCH, 93, S78 - S78

• Inflammation and underlying postoperative cognitive decline

  Conference paper

  Terrando N. et al, (2012), BRITISH JOURNAL OF ANAESTHESIA, 108, 363P - 364P

• Toll-like receptors and macrophage activation in atherosclerosis.

  Journal article

  Seneviratne AN. et al, (2012), Clinica chimica acta; international journal of clinical chemistry, 413, 3 - 14

• The tolls and dangers of atherosclerotic disease.

  Journal article

  Monaco C., (2012), Current pharmaceutical biotechnology, 13, 77 - 87

• Resolving postoperative neuroinflammation and cognitive decline.

  Journal article

  Terrando N. et al, (2011), Annals of neurology, 70, 986 - 995

• Expression of the regulatory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis

  Conference paper

  Falck-Hansen M. et al, (2011), IMMUNOLOGY, 135, 109 - 109

• A protective role for toll-like receptor 3 but not toll-like receptor 7 in intimal hyperplasia

  Conference paper

  Cole J. et al, (2011), IMMUNOLOGY, 135, 106 - 106

• Late-phase contrast-enhanced ultrasound reflects biological features of instability in human carotid atherosclerosis.

  Journal article

  Shalhoub J. et al, (2011), Stroke, 42, 3634 - 3636

• TOLL-LIKE RECEPTOR 3 EXPRESSION IS INCREASED IN ATHEROSCLEROSIS AND CONFERS PROTECTION AGAINST EARLY ATHEROSCLEROTIC LESION DEVELOPMENT AND WEIGHT GAIN IN APOLIPOPROTEIN E DEFICIENT MICE

  Journal article

  Cole JE. et al, (2011), HEART, 97, 1 - 1

• Targeting inflammation as a therapeutic strategy in accelerated atherosclerosis in rheumatoid arthritis.

  Journal article

  Full LE. and Monaco C., (2011), Cardiovascular therapeutics, 29, 231 - 242

• ANTI TNF THERAPY IN RHEUMATOID ARTHRITIS

  Conference paper

  Feldmann M. et al, (2011), INFLAMMATION RESEARCH, 60, 31 - 31

• Comparative lipidomics profiling of human atherosclerotic plaques.

  Journal article

  Stegemann C. et al, (2011), Circulation. Cardiovascular genetics, 4, 232 - 242

• Multi-analyte profiling and pathway analysis reveals a predominance of pro-inflammatory M1-type macrophage polarisation and evidence of IL17/TH17 signalling in symptomatic human carotid atherosclerosis

  Conference paper

  Shalhoub J. et al, (2011), BRITISH JOURNAL OF SURGERY, 98, 2 - 2

• Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritis.

  Journal article

  Monaco C. et al, (2011), Arthritis care & research, 63, 500 - 511

• Unexpected protective role for Toll-like receptor 3 in the arterial wall.

  Journal article

  Cole JE. et al, (2011), Proceedings of the National Academy of Sciences of the United States of America, 108, 2372 - 2377

• Intra-plaque production of M1-type cytokines and matrix metalloproteinases differentiate stable from unstable carotid atherosclerosis

  Conference paper

  Shalhoub J. et al, (2011), BRITISH JOURNAL OF SURGERY, 98, 3 - 3

• Innate immunity meets arteriogenesis: the versatility of toll-like receptors.

  Journal article

  Monaco C., (2011), Journal of molecular and cellular cardiology, 50, 9 - 12

• Imaging of the vulnerable carotid plaque: biological targeting of inflammation using ultrasmall superparamagnetic particles of iron oxide (USPIO) and MRI

  Conference paper

  Chan J. et al, (2011), BRITISH JOURNAL OF SURGERY, 98, 5 - 5

• Innate immunity and monocyte-macrophage activation in atherosclerosis.

  Journal article

  Shalhoub J. et al, (2011), Journal of inflammation (London, England), 8

• Tumor necrosis factor-alpha (TNF) triggers a cytokine cascade yielding postoperative cognitive decline

  Conference paper

  Terrando N. et al, (2010), IMMUNOLOGY, 131, 36 - 36

• Inhibitory effect of TIMP influences the morphology of varicose veins.

  Journal article

  Aravind B. et al, (2010), European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 40, 754 - 765

• Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline.

  Journal article

  Terrando N. et al, (2010), Proceedings of the National Academy of Sciences of the United States of America, 107, 20518 - 20522

• Treating atherosclerosis: the potential of Toll-like receptors as therapeutic targets.

  Journal article

  Cole JE. et al, (2010), Expert review of cardiovascular therapy, 8, 1619 - 1635

• Intra-plaque production of M1-type cytokines and matrix metalloproteinases differentiate stable from unstable carotid atherosclerosis

  Conference paper

  Shalhoub J. et al, (2010), ATHEROSCLEROSIS, 213, E17 - E18

• Imaging of the vulnerable carotid plaque: Biological targeting of inflammation using ultrasmall superparamagnetic particles of iron oxide (USPIO) and MRI

  Conference paper

  Chan J. et al, (2010), ATHEROSCLEROSIS, 213, E14 - E14

• Role of interleukin-1beta in postoperative cognitive dysfunction.

  Journal article

  Cibelli M. et al, (2010), Annals of neurology, 68, 360 - 368

• Proteomic analysis of smooth muscle cells derived from carotid plaque reveals differences between symptomatic & asymptomatic plaques

  Conference paper

  Full L. et al, (2010), EUROPEAN HEART JOURNAL, 31, 319 - 319

• VISUALISING INFLAMED ATHEROSCLEROTIC PLAQUES: MOLECULAR IMAGING USING MRI AND TARGETED ULTRASMALL SUPERPARAMAGNETIC PARTICLES OF IRON OXIDE (USPIO)

  Conference paper

  Chan J. et al, (2010), ATHEROSCLEROSIS SUPPLEMENTS, 11, 13 - 14

• The use of contrast enhanced ultrasound in carotid arterial disease.

  Journal article

  Shalhoub J. et al, (2010), European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 39, 381 - 387

• The biology of carotid plaques: once unstable, always unstable?

  Conference paper

  Sritharan K. et al, (2010), BRITISH JOURNAL OF SURGERY, 97, 1 - 1

• The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction.

  Journal article

  Terrando N. et al, (2010), Critical care (London, England), 14

• Tracking antigen-experienced effector T cells in vitro and in vivo.

  Journal article

  Gorman CL. et al, (2010), Methods in molecular biology (Clifton, N.J.), 616, 253 - 267

• The expression and functions of toll-like receptors in atherosclerosis.

  Journal article

  Cole JE. et al, (2010), Mediators of inflammation, 2010

• Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis.

  Journal article

  Monaco C. et al, (2009), Circulation, 120, 2462 - 2469

• MRI OF ENDOTHELIAL ADHESION MOLECULES IN CAROTID ATHEROSCLEROSIS USING TARGETED ULTRASMALL SUPERPARAMAGNETIC PARTICLES OF IRON OXIDE

  Conference paper

  Chan J. et al, (2009), HEART, 95

• TOLL-LIKE RECEPTOR-2 MEDIATES INFLAMMATION AND MATRIX DEGRADATION IN HUMAN ATHEROSCLEROSIS

  Journal article

  Monaco C. et al, (2009), HEART, 95

• Toll-like Receptor-2 and-4 Signaling Regulates Inflammation and Matrix Degradation in the Human Atherosclerotic Plaque

  Conference paper

  Gregan SM. et al, (2009), CIRCULATION, 120, S1138 - S1138

• VISUALISING INFLAMED ENDOTHELIAL CELLS: MOLECULAR IMAGING USING MRI AND TARGETED USPIOS

  Conference paper

  Chan J. et al, (2009), ATHEROSCLEROSIS SUPPLEMENTS, 10

• Proteomics of acute coronary syndromes.

  Journal article

  Didangelos A. et al, (2009), Current atherosclerosis reports, 11, 188 - 195

• The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus.

  Journal article

  Full LE. et al, (2009), Arthritis research & therapy, 11

• Expansion of T-cell receptor zeta dim effector T cells in acute coronary syndromes.

  Journal article

  Ammirati E. et al, (2008), Arteriosclerosis, thrombosis, and vascular biology, 28, 2305 - 2311

• C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes.

  Journal article

  Montecucco F. et al, (2008), Journal of leukocyte biology, 84, 1109 - 1119

• Additive prognostic value of interleukin-6 at peak phase of dobutamine stress echocardiography in patients with coronary artery disease. A 6-year follow-up study.

  Journal article

  Ikonomidis I. et al, (2008), American heart journal, 156, 269 - 276

• Membrane type-1 matrix metal loproteinase is upregulated in symptomatic carotid atherosclerotic disease and along with other members of the quartenary complex regulated by pro-inflammatory cytolkines

  Conference paper

  Sritharan K. et al, (2008), BRITISH JOURNAL OF SURGERY, 95, 934 - 934

• Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems.

  Journal article

  Lundberg AM. et al, (2007), Blood, 110, 3245 - 3252

• Cytokine and toll-like receptor dependent signalling in neointimal smooth muscle cells

  Conference paper

  Finch JR. et al, (2007), ATHEROSCLEROSIS, 193, S3 - S3

• NF-kappa B inhibition by blockade of IKK-2 and MYD88 in vein graft smooth muscle cells reduces the expression of key mediators of intimal hyperplasia

  Conference paper

  Finch J. et al, (2007), HEART, 93, A24 - A25

• TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues.

  Journal article

  Zhang Z. et al, (2007), Blood, 109, 4328 - 4335

• Tcrz(dim) lymphocytes define circulating effector cells that migrate to inflamed tissue

  Conference paper

  Gorman CL. et al, (2007), RHEUMATOLOGY, 46, I44 - I44

• TCR-zeta dim T cells define a population of circulating effector cells that migrate to inflamed tissues

  Conference paper

  Gorman CL. et al, (2007), ANNALS OF THE RHEUMATIC DISEASES, 66, A17 - A17

• Fluorescence lifetime imaging of unstained human atherosclerotic plaques

  Conference paper

  Hegyi L. et al, (2007), HEART, 93

• TF ligation by factor VIIa induces pro-inflammatory cytokine production in atheroma smooth muscle cells

  Conference paper

  Persson L. et al, (2006), EUROPEAN HEART JOURNAL, 27, 455 - 455

• Expansion of zeta-dim CD4+ T-cells and zeta-dim natural-killer (NK)-cells correlates with C-reactive protein (CRP) in patients with acute coronary syndromes (ACS)

  Conference paper

  Ammirati E. et al, (2006), EUROPEAN HEART JOURNAL, 27, 971 - 971

• Cytokines for myocardial ischaemia: a echocardiographic study

  Conference paper

  Raisakis K. et al, (2006), EUROPEAN HEART JOURNAL, 27, 561 - 561

• Inhibition of tissue factor signalling reduces production of pro-inflammatory cytokines in atheroma smooth muscle cells

  Conference paper

  Persson L. et al, (2006), ATHEROSCLEROSIS SUPPLEMENTS, 7, 92 - 93

• Fluorescence lifetime imaging of unstained human atherosclerotic plaques

  Conference paper

  Hegyi L. et al, (2006), ATHEROSCLEROSIS SUPPLEMENTS, 7, 587 - 587

• Enrichment of Z-dim CD4+ T-cells correlates with C-reactive protein (CRP) in patients with acute coronary syndrome (ACS)

  Conference paper

  Ammirati E. et al, (2006), ATHEROSCLEROSIS SUPPLEMENTS, 7, 86 - 86

• T cells expressing low levels of TCRzeta preferentially migrate to sites of inflammation

  Conference paper

  Gorman C. et al, (2006), ANNALS OF THE RHEUMATIC DISEASES, 65, A31 - A31

• T cells expressing low levels of TCR xi preferentially migrate to sites of inflammation

  Conference paper

  Gorman CL. et al, (2006), RHEUMATOLOGY, 45, I17 - I18

• Down-regulation of zeta-chain in CD4(+)T-cells and in natural killer cells in patients with acute coronary syndrome (ACS)

  Conference paper

  Ammirati E. et al, (2006), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 47, 328A - 328A

• What causes acute coronary syndromes? Applying Koch's postulates.

  Journal article

  Monaco C. et al, (2005), Atherosclerosis, 179, 1 - 15

• Persistent systemic inflammation in unstable angina is largely unrelated to the atherothrombotic burden.

  Journal article

  Monaco C. et al, (2005), Journal of the American College of Cardiology, 45, 238 - 243

• Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis.

  Journal article

  Monaco C. et al, (2004), Proceedings of the National Academy of Sciences of the United States of America, 101, 5634 - 5639

• Protective role of low C-reactive protein levels against classical risk factors for coronary atherosclerotic disease

  Conference paper

  Cianflone D. et al, (2004), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43, 293A - 293A

• Chlamydia pneumoniae heat shock protein 60 induces a highly specific persistent immune response in patients with unstable angina independently from IgG and IgA seropositivity

  Conference paper

  Cianflone D. et al, (2004), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43, 489A - 489A

• Nuclear factor kappaB: a potential therapeutic target in atherosclerosis and thrombosis.

  Journal article

  Monaco C. and Paleolog E., (2004), Cardiovascular research, 61, 671 - 682

• Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.

  Journal article

  Andreakos E. et al, (2004), Blood, 103, 2229 - 2237

• T-cell-mediated signalling in immune, inflammatory and angiogenic processes: the cascade of events leading to inflammatory diseases.

  Journal article

  Monaco C. et al, (2004), Current drug targets. Inflammation and allergy, 3, 35 - 42

• Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy.

  Journal article

  Andreakos E. et al, (2003), Arthritis and rheumatism, 48, 1901 - 1912

• REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN RHEUMATOID ARTHRITIS BY THE TRANSCRIPTION FACTOR NF kappa B

  Conference paper

  Kiriakidis S. et al, (2003), RHEUMATOLOGY, 42, 42 - 43

• Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction.

  Journal article

  Andreakos E. et al, (2003), Blood, 101, 983 - 991

• VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.

  Journal article

  Kiriakidis S. et al, (2003), Journal of cell science, 116, 665 - 674

• Study of the myocardial contraction and relaxation velocities through doppler tissue imaging echocardiography. Anew alternative in the assessment of the segmental ventricular function

  Journal article

  Silva CES. et al, (2002), Arquivos Brasileiros de Cardiologia, 78, 206 - 211

• Direct analysis of gene expression and regulation in human atherosclerotic tissue: Nuclear factor kappa B regulates production of cytokines and tissue factor

  Conference paper

  Monaco C. et al, (2002), CIRCULATION, 106, 259 - 259

• Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?

  Journal article

  Feldmann M. et al, (2002), Annals of the rheumatic diseases, 61 Suppl 2, ii13 - ii18

• Inflammatory predictors of mortality in the Scandinavian Simvastatin Survival Study.

  Journal article

  Crea F. et al, (2002), Clinical cardiology, 25, 461 - 466

• Inhibition of VEGF in human macrophages and rheumatoid synovial cells by blockade of the NF kappa B pathway using adenoviral gene transfer

  Conference paper

  Kiriakidis S. et al, (2002), JOURNAL OF MOLECULAR MEDICINE-JMM, 80, B3 - B3

• T cell-mediated signaling to vascular endothelium: induction of cytokines, chemokines, and tissue factor.

  Journal article

  Monaco C. et al, (2002), Journal of leukocyte biology, 71, 659 - 668

• VEGF EXPRESSION IN HUMAN MACROPHAGES IS NF kappa B-DEPENDENT: STUDIES USING ADENOVIRUSES EXPRESSING A KINASE DEFECTIVE FORM OF IKK2 or I kappa B alpha THE NATURAL NF kappa B INHIBITOR

  Conference paper

  Kiriakidis S. et al, (2002), RHEUMATOLOGY, 41, 66 - 66

• SELECTIVE USAGE OF IKK2 FOR NF-kappa B ACTIVATION AND PRO-INFLAMMATORY GENE EXPRESSION: STUDIES IN HUMAN PRIMARY CELLS AND RHEUMATOID SYNOVIAL MEMBRANE CELL CULTURES

  Conference paper

  Andreakos E. et al, (2002), RHEUMATOLOGY, 41, 65 - 65

• REQUIREMENT FOR NF kappa B AND IKK-2 IN TISSUE FACTOR EXPRESSION BY CELLS RELEVANT TO THE PATHOGENESIS OF ATHEROSCLEROSIS AND RHEUMATOID ARTHRITIS

  Conference paper

  Monaco C. et al, (2002), RHEUMATOLOGY, 41, 32 - 32

• Risk of myocardial infarction and angina in patients with severe peripheral vascular disease: predictive role of C-reactive protein.

  Journal article

  Rossi E. et al, (2002), Circulation, 105, 800 - 803

• VEGF expression in human macrophages is NFkB-dependent: studies using adenoviral gene transfer

  Conference paper

  Kiriakidis S. et al, (2002), EUROPEAN HEART JOURNAL, 23, 382 - 382

• NFkB and IkB kinase-2 regulate tissue factor and cytokine production in human atherosclerotic plaques: an analysis via adenoviral gene transfer

  Conference paper

  Monaco C. et al, (2002), EUROPEAN HEART JOURNAL, 23, 261 - 261

• Inhibition of tissue factor by blockade of NFkB and IKK-2 using gene transfer: NFkB as a therapeutic target for reducing plaque thrombogenicity

  Conference paper

  Monaco C. et al, (2002), EUROPEAN HEART JOURNAL, 23, 20 - 20

• Autoantibodies against oxidized low density lipoproteins in patients with stable angina, unstable angina or peripheral vascular disease; pathophysiological implications.

  Journal article

  Monaco C. et al, (2001), European heart journal, 22, 1572 - 1577

• [Cellular mechanisms of regulation of the inflammatory response in atherosclerosis: the role of cell contact-mediated signaling]

  Journal article

  Monaco C. et al, (2001), Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2, 339 - 343

• Inhibition of tissue factor induction by blockade of the nuclear factor-kappa B pathway in human macrophages and endothelial cells using adenoviral gene transfer: Nuclear factor-kappa B as a potential therapeutic target for plaque stabilization

  Journal article

  Monaco C. et al, (2001), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 37, 289A - 289A

• Inflammatory predictors of mortality in the Scandinavian Simvastatin Survival Study

  Conference paper

  Crea F. et al, (2000), CIRCULATION, 102, 699 - 699

• Activated T-cells stimulate endothelial cells to release proinflammatory cytokines in a contact-dependent manner: A clue about the pathogenesis of atherosclerosis?

  Conference paper

  Monaco C. et al, (2000), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 35, 316A - 317A

• Chemokine production from endothelial cells is induced by activated T cells in a contact-dependent manner: a role for cell-cell contact interactions in the pathogenesis of atherosclerosis

  Conference paper

  Monaco C. et al, (2000), EUROPEAN HEART JOURNAL, 21, 158 - 158

• Anti-oxidized LDL antibodies levels in patients with stable angina, unstable angina and peripheral vascular disease: pathophysiological implications

  Journal article

  Monaco C. et al, (2000), EUROPEAN HEART JOURNAL, 21, 655 - 655

• Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

  Journal article

  Monaco C., Atherosclerosis

Recent Publications

• Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

  Journal article

  Seneviratne AN. et al, (2017), Circulation, 136, 1140 - 1154

• Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia.

  Journal article

  Berbée JFP. et al, (2017), Atherosclerosis, 264, 100 - 107

• Imaging vulnerable plaques by targeting inflammation in atherosclerosis using fluorescent-labeled dual-ligand microparticles of iron oxide and magnetic resonance imaging.

  Journal article

  Chan JMS. et al, (2017), Journal of vascular surgery

• Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques.

  Journal article

  Langley SR. et al, (2017), The Journal of clinical investigation, 127, 1546 - 1560

• Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".

  Journal article

  Weber C. et al, (2016), Thrombosis and haemostasis, 116, 626 - 637