Simon Abram
MA(Oxon) BMBCh FRCS(T&O) MAcadMEd MBA DPhil
Senior Clinical Lecturer & Consultant Knee Surgeon
Simon graduated from Oxford University medical school in 2010 and began surgical training in Trauma and Orthopaedics in 2012. From 2016-19, Simon took time out of surgical training to undertake a DPhil (PhD) aimed at improving the treatment of patients with meniscal tears of the knee. In support of this work, Simon was awarded a nationally competitive Doctoral Research Fellowship by the NIHR in 2017.
Simon’s research currently has four main themes:
1. The epidemiology of musculoskeletal conditions and surgical interventions. A number of large healthcare databases are available in the UK and this ‘big data’ represents a valuable and relatively untapped resource to inform patients and clinicians of the risks and benefits of orthopaedic interventions. Simon works with the national hospital episode statistics (HES) database to investigate trends and regional variation in surgical practice and to determine the short-term risks and long-term outcomes of surgical procedures. In 2023, Simon was awarded an Academy of Medical Sciences grant in further support of an expansion of this work.
2. Guideline development and treatment pathway improvement. For many orthopaedic procedures, there is apparent variation in the delivery of care between treatment centres. There is a need to standardise treatment decisions to ensure all patients receive evidence-based care and to consistently monitor and improve the outcomes of this care. Simon previously worked to deliver a national treatment guideline for the management of meniscal tears of the knee, in collaboration with Professor Andrew Price, Professor David Beard, and the British Association for Surgery of the Knee (BASK).
3. Healthcare operations and resource management. Waiting lists in the UK are at an all time high and there is a need to improve efficiency in provision of hip and knee replacement. 'High-volume' surgical pathways aim to treat more patients within the constraints of current resources. Through this theme, Simon is working to deliver refinements to the pre-surgical, surgical, and post-surgical processes to improve patient treatment flow and efficiency.
4. AI-enhanced surgical planning. The utilisation of artificial intelligence in the planning of the technical aspects of surgical procedures is an emerging area. Simon is interested in the application of AI in planning for and evaluating surgical interventions. Specifically, Simon is interested in combining AI-enhanced imaging analysis with patient data, clinical outcome data, biomechanical assessments and modelling to deliver tools that have the potential to improve surgical outcomes.
In addition to these core research themes, Simon is a co-investigator for the NIHR EME funded GEKO trial to evaluate geniculate artery embolisation for painful knee osteoarthritis and previously supported the ACL-SNNAP trial in Oxford. Simon also has an interest in orthopaedic infection and is collaborating with biomedical engineering and bioengineering colleagues on this topic, currently working on creating an implant retrieval pipeline for infected implant materials. Simon is a DPhil co-supervisor and examines and teaches for Oxford University medical school.
Key publications
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Adverse outcomes after arthroscopic partial meniscectomy: a study of 700 000 procedures in the national Hospital Episode Statistics database for England.
Journal article
Abram SGF. et al, (2018), Lancet, 392, 2194 - 2202
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National consensus on the definition, investigation, and classification of meniscal lesions of the knee.
Journal article
Abram SGF. et al, (2018), Knee, 25, 834 - 840
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Arthroscopic partial meniscectomy for meniscal tears of the knee: a systematic review and meta-analysis.
Journal article
Abram SGF. et al, (2020), Br j sports med, 54, 652 - 663
Recent publications
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Use of dual-energy X-ray absorptiometry to evaluate variation in bone shape and alignment associated with radiographic knee osteoarthritis: findings from a study of 19,053 individuals in UK Biobank
Journal article
Beynon RA. et al, (2025), Osteoarthritis and cartilage open, 100667 - 100667
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Comparison of surgical or non-surgical management for non-acute anterior cruciate ligament injury: the ACL SNNAP RCT.
Journal article
Beard DJ. et al, (2024), Health technol assess, 28, 1 - 97
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Patient-Relevant Outcomes Following First Revision Total Knee Arthroplasty, by Diagnosis: An Analysis of Implant Survivorship, Mortality, Serious Medical Complications, and Patient-Reported Outcome Measures Utilizing the National Joint Registry Data Set.
Journal article
Sabah SA. et al, (2023), J bone joint surg am, 105, 1611 - 1621
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Consensus statement on unicompartmental knee replacement: A collaboration between BASK and EKS.
Journal article
Price A. et al, (2023), Knee, 41, 391 - 396
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Patella denervation with circumferential electrocautery in primary knee arthroplasty: a randomized controlled trial
Journal article
Spencer SJ. et al, (2023), The journal of arthroplasty