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Siobhan Webb


I graduated from Cardiff University in 2012 with a PhD in Cancer Biology. My thesis focused on a serine protease, Matriptase-2, and it's role in prostate cancer and angiogenesis. Within the Edwards group I now  research Multiple Myeloma, an incurable cancer in which the healthy bone marrow is overtaken with malignant myeloma cells. 

My research focuses on the bone marrow micro-environment and how the myeloma cells interact with the healthy bone marrow cells. I am investigating how the bone marrow micro-environment can affect the response of myeloma cells to current and new anticancer treatments. As many patients experience resistance to conventional drugs, the search for new treatments is essential. I am also examining how adiponectin, an adipokine, can be used singly and in combination with current therapies to kill myeloma cells.