National Rheumatoid Arthritis Society webinar
Christopher Buckley
Kennedy Professor of Translational Rheumatology and Director of Clinical Research
Chris Buckley obtained his first degree in Biochemistry from the University of Oxford (1985) with subsequent undergraduate training in Medicine at the Royal Free Hospital, London (1990).
His postgraduate medical training was in General Medicine and Rheumatology at the Hammersmith Hospital, London (Professors Mark Walport and Dorian Haskard), and John Radcliffe Hospital, Oxford. He obtained a DPhil (arising from a Wellcome Trust Clinical Training Fellowship) with Professor John Bell and Dr David Simmons at the Institute Molecular Medicine, Oxford.
In 1996, funded by a Wellcome Trust Clinician Scientist Fellowship, he joined the Department of Rheumatology in Birmingham. In 2001, he was awarded an MRC Senior Clinical Fellowship and in 2002 became Arthritis Research UK Professor of Rheumatology. In 2012, he was appointed Director of the Birmingham NIHR Clinical Research Facility. And in May 2017, he was appointed as Kennedy Professor of Translational Rheumatology.
In this joint academic post as Director of Clinical Research at the Kennedy Institute in Oxford and Director of NIHR Infrastructure for Birmingham Heath Partners he will lead the Arthritis Therapy Acceleration Programme (A-TAP) which aims to deliver “stratified pathology” in a range of immune mediated inflammatory diseases in order to choose the right disease indication for the right drug.
This approach complements stratified medicine where the aim is to choose the right drug for the right patient. As part of the Stromal Cell group at the Kennedy, his laboratory explores the role of fibroblasts in driving disease progression and tissue tropism in Rheumatoid Arthritis..
Recent publications
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                Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy.Journal article Wang Y-J. et al, (2025), Sci transl med, 17 
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                Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity.Journal article Bolton C. et al, (2025), Sci transl med, 17 
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                Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis.Journal article Lewis MJ. et al, (2025), Nature communications, 16 
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                Cellular and molecular landscapes of human tendons across the lifespan revealed by spatial and single-cell transcriptomicsPreprint Kurjan A. et al, (2025) 
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                CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue.Journal article Liu F. et al, (2025), Ann rheum dis