Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Congratulations to Mariana Borsa for being awarded the Marie Skłodowska-Curie Actions – Individual Fellowship

Mariana Borsa

Kennedy Institute researcher Mariana Borsa has been awarded a prestigious Marie Curie Fellowship to further develop her research at the boundary between cell biology and immunology.

The two-year Marie Skłodowska-Curie Actions – Individual Fellowship (MSCA – IF) will support Mariana's study into the role of autophagy, a pathway responsible for degradation and recycling of cellular components, in the differentiation of healthy blood cells (the hematopoietic system). The haematopoietic system relies on the potential of haematopoietic stem cells (HSCs) to self-renew and differentiate into all lineages of mature blood cells, and degradation pathways play relevant roles in fate determination.

Commenting on the award, Mariana said: "I plan to test the hypothesis that autophagy has an early impact on haematopoiesis, determining the decision between maintenance of stem cells and fate commitment (differentiation) in HSCs. My efforts will particularly focus on understanding how asymmetric inheritance of autophagy during cell division influences cell fate. I hope modulation of this mechanism can be a target for future therapeutic use in humans, especially in the context of regenerative medicine and ageing. I am absolutely honoured to be a Marie Curie Fellow, and also sure this fellowship will boost my career development towards becoming an independent scientist."

Mariana will undertake the project under the guidance of Prof. Katja Simon, a pioneer in the field of autophagy in the haematopoietic system, and will have Prof. Sten Eirik Jacobsen (Karolinska Institute) and Prof. Pekka Katajisto (University of Helsinki) as collaborators.

Similar stories

Professor Sir Gordon Duff receives Honorary Senior Fellowship at NDORMS

Professor Sir Gordon Duff has been awarded an Honorary Senior Fellowship at NDORMS.

Oxford researchers call for an urgent re-evaluation of “weak” opioid safety profile

A new study associates dispensation doses of tramadol with increased risk of mortality, cardiovascular events, and fractures compared to the use of codeine to treat pain.

New therapeutic targets identified to treat inflammatory bowel disease

Millions of patients with ulcerative colitis or Crohn’s disease, collectively known as inflammatory bowel disease (IBD), are given fresh hope as a new study shows why some of them do not respond to current treatments.

Afsie Sabokbar wins Lifetime Achievement at Teaching Excellence Awards

Director of Graduate Studies Afsie Sabokbar wins Lifetime Achievement at 2021 Teaching Excellence Awards.

NDORMS staff recognised in the 2021 Teaching Excellence Awards

Director of Graduate Studies Afsie Sabokbar, Associate Professor Stephanie Dakin and Graduate Studies Officer Samuel Burnell were all winners in the Teaching Excellence Awards.

Five ways to take action for your bone health

On World Osteoporosis Day, the International Osteoporosis Foundation (IOF), the world’s largest non-governmental organisation in the bone field, urges action for osteoporosis and fracture prevention.