CPinBOSS study findings

CPinBOSS study - Our Findings.

A National Prospective Cohort Study on the Effects of Single Event Multi-Level Surgery on Gait and Function in Children with Diplegic Cerebral Palsy.

Section 1: What was the CPinBOSS Study?

The CPinBOSS study looked at how well a surgery called SEMLS, Single-Event Multi-Level Surgery, works for children with Cerebral Palsy, CP. This surgery helps straighten the legs and is thought to improve walking.

Section 2: Why was the CPinBOSS Study done?

SEMLS involves several operations at the same time, followed by rehabilitation. Hospitals across the UK do SEMLS differently, and we didn’t have detailed information about how well it worked. The study collected information about the surgery and how children recovered.

Section 3: What did the CPinBOSS Study involve?

Point 1:
All UK hospitals doing SEMLS took part. They collected information on children having the surgery and followed their recovery for 2 years.

Point 2:
Information was also collected on children who could potentially benefit from SEMLS but didn’t have the surgery so we could compare the results.

Point 3:
Parents and children filled in questionnaires about how well they were doing after treatment.

Study Numbers:

203 children joined the study; 139 had SEMLS surgery. At the end of the study, 188 children’s data was looked at.
On average, 5 procedures were done during each surgery.
Complications happened in 18 percent of cases, most of which had no lasting effects.

Section 4: What were the main findings of CPinBOSS?

Finding 1:
Surgery appeared to make walking straighter and more upright, as measured by gait analysis using computers.

Finding 2:
Parents suggested that their children’s walking improved, though changes in walking speed and distance were small.

Finding 3:
It appeared that children who did not have surgery got worse with their walking over time.

Section 5: What did we learn from the CPinBOSS Study?

Hospitals handle SEMLS differently.
We found a clear signal to suggest an improvement in function following SEMLS.
Different hospital teams need to get better at collecting the same information as each other, both before and after surgery. This will make future nationwide studies easier.