Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Publications

A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation.

Bao C. et al, (2024), Cell rep methods

Priority index for critical Covid-19 identifies clinically actionable targets and drugs.

Zhang Z. et al, (2024), Commun biol, 7

Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers.

Barton A. et al, (2022), Infect immun

Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis.

Vecellio M. et al, (2021), Arthritis rheumatol, 73, 980 - 990

From the Genetics of Ankylosing Spondylitis to New Biology and Drug Target Discovery.

Nancy Z. et al, (2021), Front immunol, 12

Identification of an Unconventional Subpeptidome Bound to the Behçet's Disease-associated HLA-B*51:01 that is Regulated by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1).

Chen L. et al, (2020), Mol cell proteomics, 19, 871 - 883

Identification of an Unconventional Subpeptidome Bound to the Behçet's Disease-associated HLA-B*51:01 that is Regulated by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1).

Chen L. et al, (2020), Mol cell proteomics, 19, 871 - 883

From genome-wide association studies to rational drug target prioritisation in inflammatory arthritis

Fang H. et al, (2020), The lancet rheumatology, 2, e50 - e62

GM-CSF Primes Proinflammatory Monocyte Responses in Ankylosing Spondylitis.

Shi H. et al, (2020), Front immunol, 11

A genetics-led approach defines the drug target landscape of 30 immune-related traits.

Fang H. et al, (2019), Nat genet, 51, 1082 - 1091

OP0231?Differential transcription factor binding could explain the genetic association of ankylosing spondylitis with polymorphisms in the IL23R-IL12RB2 intergenic region

(2018), Annals of the rheumatic diseases

Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases.

Hammitzsch A. et al, (2018), Sci rep, 8

Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators.

Lagou V. et al, (2018), Cell rep, 25, 798 - 810.e6

Is Behçet's disease a 'class 1-opathy'? The role of HLA-B*51 in the pathogenesis of Behçet's disease.

Giza M. et al, (2018), Clin exp immunol, 191, 11 - 18

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis.

Al-Mossawi MH. et al, (2017), Nat commun, 8

A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis.

Schwerd T. et al, (2017), J exp med, 214, 2547 - 2562

Deficiency of filaggrin regulates endogenous cysteine protease activity, leading to impaired skin barrier function.

Wang XW. et al, (2017), Clin exp dermatol, 42, 622 - 631

GTP cyclohydrolase accelerates tumor progression through interaction with angiopoietin-1 in stromal fibroblasts and activation of Tie2 on breast cancer cells

CAI S. et al, (2017)

miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis.

Chen L. et al, (2017), Ann rheum dis, 76, 620 - 625

Position 97 of HLA-B, a residue implicated in pathogenesis of ankylosing spondylitis, plays a key role in cell surface free heavy chain expression.

Chen L. et al, (2017), Ann rheum dis, 76, 593 - 601

Load More

Include forthcoming?