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The FAME trial has been given the green light and is now open to recruitment.

The FAME (Fractured Ankle Management Evaluation) Trial has now received OCTRU Green Light approval to start recruitment!


This trial is comparing two different types of treatment for a broken ankle – a close contact cast to hold the bones correctly while they heal versus an operation where the broken bones are held using plates and screws. The trial aims to recruit 890 patients across at least 20 NHS hospitals.