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Osteomalacia is commonly found in patients with severe renal impairment. Its aetiology is multifactional and not simply due to deficient production of active metabolites of vitamin D. Decreased availability of calcium and phosphate and the accumulation of aluminium is some dialysis-treated patients are also important aetiological factors. The treatment of osteomalacia depends, in part, upon its accurate diagnosis, and identifying and reversing the underlying cause.

Original publication

DOI

10.1185/03007998109114275

Type

Journal article

Journal

Curr med res opin

Publication Date

1981

Volume

7

Pages

294 - 315

Keywords

Calcium, Humans, Kidney Diseases, Kidney Failure, Chronic, Osteomalacia, Phosphates, Trace Elements, Vitamin D, Water Pollutants, Chemical