The role of vitamin D metabolites in the osteomalacia of renal disease.
Kanis JA., Brown CB., Cameron EC., Cundy T., Platts MM., Paterson M., Russell RG.
Osteomalacia is commonly found in patients with severe renal impairment. Its aetiology is multifactional and not simply due to deficient production of active metabolites of vitamin D. Decreased availability of calcium and phosphate and the accumulation of aluminium is some dialysis-treated patients are also important aetiological factors. The treatment of osteomalacia depends, in part, upon its accurate diagnosis, and identifying and reversing the underlying cause.