Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Trigger finger is due to degeneration and thickening of the proximal portion (A1 pulley) of the flexor tendon sheath, which causes constriction of the flexor tendon. This study reports the presence of localized amyloid deposition in the tendon sheath of 11 of 47 cases (23%) of idiopathic primary trigger finger. Amyloid deposits were only found in patients aged over 46 years old and were present around cells and at sites of mucinous and fibrinoid degeneration which contained highly sulphated glycosaminoglycans. The pathogenic significance of these deposits is uncertain but their small size and presence only in middle-aged and elderly adults suggests that they represent a form of age-associated amyloid deposition.

Original publication

DOI

10.1054/jhsb.2001.0571

Type

Journal article

Journal

Journal of hand surgery (Edinburgh, Scotland)

Publication Date

08/2001

Volume

26

Pages

380 - 383

Addresses

Nuffield Orthopaedic Centre, Oxford, UK.

Keywords

Fingers, Tendons, Humans, Muscular Diseases, Amyloid, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male