Enhanced efficacy in drug-resistant cancer cells through synergistic nanoparticle mediated delivery of cisplatin and decitabine
Parhizkar M., Reardon PJT., Harker AH., Browning RJ., Stride E., Pedley RB., Knowles JC., Edirisinghe M.
<p>Co-encapsulation of cisplatin and decitabine in nanoparticles produced by electrohydrodynamic processing. Combination of multiple therapeutic agents in a single nano-carrier could potentially help to overcome drawbacks of monotherapy in cancer treatment.</p>