Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Aging changes in different body system are well described, but few studies have considered the relationship between them.The purpose of this study was, therefore, to investigate the interrelationships between markers of aging in different parts of the body.A cross-sectional study design was used. Structural and functional markers of aging were measured in a number of different body systems.Conditional independence analysis demonstrated that the aging markers selected clustered into two groups, either related to chronological age or adult height. Visual acuity, lens opacity, hearing threshold, cognitive decline, and the number of teeth were associated with age, while systolic blood pressure and skin thickness were related to height. Grip strength was associated with both.The differential associations of the aging markers with chronological age and adult height suggest that different systems do not age together. This may have relevance for understanding what underlies aging, and these preliminary findings now require replication in other aging cohorts.

Original publication

DOI

10.1159/000022068

Type

Journal article

Journal

Gerontology

Publication Date

01/1999

Volume

45

Pages

83 - 86

Addresses

MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK. aas@mrc.soton.ac.uk

Keywords

Humans, Body Weight, Body Height, Cohort Studies, Cross-Sectional Studies, Cognition, Sex Factors, Aging, Blood Pressure, Visual Acuity, Aged, Female, Male, Biomarkers