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We describe a patient with relapsing polychondritis who developed fatal cardiac involvement comprising complete heart block, acute aortic incompetence, and cardiovascular collapse. Pathologic studies showed fibrosis of the cardiac conducting system and necrotizing inflammation of the aortic valve, features not previously described in relapsing polychondritis, as well as evidence of coronary artery vasculitis.

Original publication

DOI

10.1002/art.1780340115

Type

Journal article

Journal

Arthritis and rheumatism

Publication Date

01/1991

Volume

34

Pages

97 - 100

Addresses

Department of Medicine, Hammersmith Hospital, London, UK.

Keywords

Aortic Valve, Humans, Polychondritis, Relapsing, Heart Block, Aortic Valve Insufficiency, C-Reactive Protein, Echocardiography, Adult, Male