Biologic therapies for rheumatoid arthritis targeting TNF-α and IL-1
Taylor PC.
'Biologics' are protein-based drugs derived from living organisms and are designed to either inhibit or augment a specific component of the immune system. Examples include antibodies directed against very specific molecular components of the immune response, for example, pro-inflammatory cytokines, or naturally occurring cytokine inhibitors such as IL-1 receptor antagonist (IL-1ra). © 2007 Springer-Verlag Berlin Heidelberg.