Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Nonlinear propagation of ultrasound through microbubble populations can generate artifacts and reduce contrast to tissue ratio in ultrasound imaging. The existing propagation model, which underestimates harmonic generation by an order of magnitude, was revised by incorporating a nonlinear constitutive equation for the coating into the description of the microbubble dynamics. Significantly better agreement with experiments was obtained, indicating that coating nonlinearity represents an important contribution to nonlinear propagation of ultrasound in microbubble populations. The results were found to be sensitive to the parameters characterizing the coating nonlinearity and thus accurate measurement of these parameters is required for accurate quantitative predictions.

Original publication

DOI

10.1121/1.3544677

Type

Journal article

Journal

The Journal of the Acoustical Society of America

Publication Date

03/2011

Volume

129

Pages

EL76 - EL82

Addresses

Department of Bioengineering, Imperial College London, London SW7 2AZ, United Kingdom. mengxing.tang@ic.ac.uk

Keywords

Sulfur Hexafluoride, Phospholipids, Contrast Media, Artifacts, Reproducibility of Results, Microbubbles, Surface Properties, Nonlinear Dynamics, Sound, Ultrasonics, Motion, Pressure, Computer Simulation, Numerical Analysis, Computer-Assisted