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A patient is described with chronic neutropenia who was followed for 22 years. She had varying patterns of neutropenia, sometimes cyclical, sometimes almost agranulocytic; at times the counts were normal. The course was complicated by a vasculitis and finally by large vessel thrombosis; extensive amyloid was found in small vessels at necropsy.

Original publication

DOI

10.1136/jcp.26.8.592

Type

Journal article

Journal

J clin pathol

Publication Date

08/1973

Volume

26

Pages

592 - 595

Keywords

Adolescent, Adult, Agranulocytosis, Amyloidosis, Female, Gangrene, Humans, Leukocyte Count, Neutrophils, Pulmonary Embolism, Splenectomy, Steroids, Stress, Psychological, Vascular Diseases