Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Dendritic cells prepared by a modification of the method of Steinman and Cohn are I-A+ and FcR-. They are extremely potent at activating not only allogeneic T cell proliferation but also antigen-specific syngeneic T cell proliferation. Dendritic cells from nonresponder strains are unable to present antigens to responder X nonresponder T cells, suggesting that they may be a site of Ir gene product expression.

Original publication

DOI

10.1084/jem.152.6.1817

Type

Journal article

Journal

The Journal of experimental medicine

Publication Date

12/1980

Volume

152

Pages

1817 - 1822

Keywords

Lymph Nodes, Spleen, T-Lymphocytes, Animals, Mice, Antigens, Histocompatibility Antigens Class II, Cell Separation, Lymphocyte Activation, Genes, MHC Class II