Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The interaction of activated leukocytes with the rheumatoid synovial environment is a key process in arthritis. Understanding this process will play an important role in designing effective treatments. In vivo imaging approaches combined with molecular genetics in animal models provide important tools to address these issues. The present review will focus on approaches to in vivo imaging, with particular attention to approaches that are proving useful for, or have promise for, research on animal models of rheumatoid arthritis. These approaches will probably shed light on the specific local mechanisms involved in chronic inflammation and provide real time monitoring approaches to follow cellular and molecular events related to disease development.

Original publication

DOI

10.1186/ar768

Type

Journal article

Journal

Arthritis research & therapy

Publication Date

01/2003

Volume

5

Pages

165 - 171

Addresses

Skirball Institute of Biomolecular Medicine and Department of Pathology, New York University School of Medicine, New York, USA. dustin@saturn.med.nyu.edu

Keywords

Leukocytes, Animals, Arthritis, Rheumatoid, Disease Models, Animal, Microscopy, Tomography, Luminescent Measurements, Cell Movement