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The recent Juan March Foundation meeting on "Regulation and functional insights in cellular polarity" focused on cellular polarity in yeasts, Dictyostelium, epithelial cells, fibroblasts, and immune cells. The molecular systems covered included membrane rafts, actin and tubulin cytoskeleton, polarized transcription, signaling, and cell-cell adhesion. Across these diverse biological and molecular systems, important general concepts emerged, including new ideas for establishing and maintaining polarity that are likely to be applicable across models and experimental systems.

Original publication

DOI

10.1016/s0092-8674(02)00820-6

Type

Journal article

Journal

Cell

Publication Date

07/2002

Volume

110

Pages

13 - 18

Addresses

Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA. dustin@saturn.med.nyu.edu

Keywords

Membranes, Cytoplasm, Microtubules, Animals, Humans, Actins, Tubulin, rac GTP-Binding Proteins, Membrane Lipids, Cell Adhesion, Signal Transduction, Cell Polarity