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Induced pluripotent stem cells (iPSCs) have the potential to transform drug discovery and healthcare in the 21(st) century. However, successful commercialization will require standardized manufacturing platforms. Here we highlight the need to define standardized practices for iPSC generation and processing and discuss current challenges to the robust manufacture of iPSC products.

Original publication

DOI

10.1016/j.stem.2014.12.013

Type

Journal article

Journal

Cell stem cell

Publication Date

01/2015

Volume

16

Pages

13 - 17

Addresses

Department of Biochemical Engineering, University College London, London, WC1H 0AH, UK.

Keywords

Animals, Humans, Stem Cell Transplantation, Cell Culture Techniques, Reproducibility of Results, Induced Pluripotent Stem Cells, Cellular Reprogramming