Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

A new formulation of volatile nanodroplets stabilized by a protein and polymer coating and loaded with magnetic nanoparticles is developed. The droplets show enhanced stability and phase conversion efficiency upon ultrasound exposure compared with existing formulations. Magnetic targeting, encapsulation, and release of an anticancer drug are demonstrated in vitro with a 40% improvement in cytotoxicity compared with free drug.

Original publication

DOI

10.1002/adma.201502022

Type

Journal article

Journal

Adv mater

Publication Date

07/10/2015

Volume

27

Pages

5484 - 5492

Keywords

breast cancer, chemotherapy, microbubbles, nanodroplets, ultrasound, Antineoplastic Agents, Antineoplastic Agents, Phytogenic, Cell Survival, Drug Carriers, Drug Delivery Systems, Drug Liberation, Equipment Design, Ferric Compounds, Fluorocarbons, Humans, MCF-7 Cells, Magnetite Nanoparticles, Oleic Acid, Paclitaxel, Polyethylene Glycols, Quaternary Ammonium Compounds, Serum Albumin, Ultrasonography