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Anti-TNFalpha therapy may have associated risks of serious infection, congestive heart failure, malignancy, and multiple sclerosis. The magnitude of these risks is difficult to assess. This article reviews publications on the current knowledge about the safety of these agents.

Original publication

DOI

10.1136/ard.2004.024737

Type

Journal article

Journal

Annals of the rheumatic diseases

Publication Date

12/2004

Volume

63

Pages

1538 - 1543

Addresses

ARC Epidemiology Unit, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

Keywords

Humans, Opportunistic Infections, Arthritis, Rheumatoid, Autoimmune Diseases, Tumor Necrosis Factor-alpha, Immunoglobulin G, Receptors, Tumor Necrosis Factor, Antirheumatic Agents, Antibodies, Monoclonal, Heart Failure