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Randomized clinical trials (RCTs) generally provide the highest quality and least biased evidence for treatment effectiveness. Relatively few high-quality RCTs have been published in the orthopaedic literature. Barriers to increasing the quantity of trials include the orthopaedic culture, patient preferences, and the availability of treatment outside trials. Challenges to conducting better quality trials include sample size, random allocation, and blinding. Undertaking more high-quality trials can improve the evidence available for determining treatment effectiveness, resulting in better patient care.

Type

Journal article

Journal

J am acad orthop surg

Publication Date

08/2010

Volume

18

Pages

454 - 463

Keywords

Humans, Organizational Culture, Orthopedic Procedures, Orthopedics, Outcome Assessment (Health Care), Randomized Controlled Trials as Topic, Research Design