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Randomized clinical trials (RCTs) generally provide the highest quality and least biased evidence for treatment effectiveness. Relatively few high-quality RCTs have been published in the orthopaedic literature. Barriers to increasing the quantity of trials include the orthopaedic culture, patient preferences, and the availability of treatment outside trials. Challenges to conducting better quality trials include sample size, random allocation, and blinding. Undertaking more high-quality trials can improve the evidence available for determining treatment effectiveness, resulting in better patient care.


Journal article


J am acad orthop surg

Publication Date





454 - 463


Humans, Organizational Culture, Orthopedic Procedures, Orthopedics, Outcome Assessment (Health Care), Randomized Controlled Trials as Topic, Research Design