Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Anecdotal observation suggested a local increase in the occurrence of scleroderma within a borough in close proximity to a major airport. Ascertainment of all living cases was attempted within that borough and adjacent boroughs as well as a similar exercise in two further boroughs in close proximity to another major airport. The results showed a higher prevalence of scleroderma in all three study areas compared to that expected based on a population survey in another part of the United Kingdom adopting similar methodology. Further, within the boroughs there was a suggestion that the cases were not uniformly distributed but tended, in part, to cluster in those parts of the study areas that were in fact near to the airports under investigation. The increase in absolute risk was not sufficiently high to be consistent with a major environmental hazard. There is also no biologically plausible hypothesis for these observations. Nevertheless, the observation is of interest and might suggest further lines of inquiry for aetiological research.

Type

Journal article

Journal

British journal of rheumatology

Publication Date

04/1990

Volume

29

Pages

93 - 96

Addresses

ARC Epidemiology Research Unit, University of Manchester Medical School.

Keywords

Humans, Scleroderma, Systemic, Prevalence, Risk Factors, Aircraft, Adolescent, Adult, London, England, Female, Male