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Recent studies have identified interleukin 10 as a differentiation factor for a novel subset of immune suppressive regulatory T cells. Here, Hervé Groux and Fiona Powrie discuss the role that these cells play in the regulation of immune responses to enteric antigens and suggest that a deficiency in these cells might be involved in the pathogenesis of inflammatory bowel disease.

Type

Journal article

Journal

Immunol Today

Publication Date

10/1999

Volume

20

Pages

442 - 445

Keywords

Animals, Cell Differentiation, Humans, Inflammatory Bowel Diseases, Interleukin-10, Mice, T-Lymphocyte Subsets