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Publications

Identification of non-conventional small molecule degraders and stabilizers of squalene synthase.

Hoock JGF. et al, (2023), Chem sci, 14, 12973 - 12983

Mechanisms of substrate processing during ER-associated protein degradation.

Christianson JC. et al, (2023), Nat rev mol cell biol, 24, 777 - 796

Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.

Kurata K. et al, (2023), Blood cancer j, 13

Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.

Kurata K. et al, (2023), Blood cancer j, 13

Order through destruction: how ER-associated protein degradation contributes to organelle homeostasis.

Christianson JC. and Carvalho P., (2022), Embo j, 41

The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation.

Kulicke CA. et al, (2022), J biol chem, 298

EMC is required for biogenesis of Xport-A, an essential chaperone of Rhodopsin-1 and the TRP channel.

Gaspar CJ. et al, (2022), Embo rep, 23

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.

Fenech EJ. et al, (2020), Elife, 9

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

Fenech EJ. et al, (2020)

Squaring the EMC: how promoting membrane protein biogenesis impacts cellular functions and organismal homeostasis

Volkmar N. and CHRISTIANSON J., (2020), Journal of cell science

Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation.

Taverner WK. et al, (2019), Mol ther oncolytics, 15, 117 - 130

Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells.

Bedard M. et al, (2019), Proc natl acad sci u s a, 116, 23671 - 23681

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

Bushell S. et al, (2019), Nat commun

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.

Bushell SR. et al, (2019), Nat commun, 10

Inadequate BiP availability defines endoplasmic reticulum stress

Vitale M. et al, (2019), Elife, 8

Inadequate BiP availability defines endoplasmic reticulum stress.

Vitale M. et al, (2019), Elife, 8

An essential role for the Zn2+ transporter ZIP7 in B cell development.

Anzilotti C. et al, (2019), Nat immunol, 20, 350 - 361

The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis.

Volkmar N. et al, (2019), J cell sci, 132

ERAD-dependent control of the Wnt secretory factor Evi.

Glaeser K. et al, (2018), Embo j, 37

The ER membrane protein complex is a transmembrane domain insertase.

Guna A. et al, (2018), Science, 359, 470 - 473

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