Gretchen Brewer
Trainee Clinical Trial Manager
I joined NDORMS in September 2019 supporting research projects led by Dr Fiona Watt in the Centre for Osteoarthritis Pathogenesis Versus Arthritis. I am currently a Clinical Study Administrator for the HOPE-e study which is investigating whether it is feasible for postmenopausal women with painful hand osteoarthritis to take an estrogen-containing therapy and the MenTOR study which is investigating meniscal tear and risk of osteoarthritis.
In my previous role, I worked as a Research Assistant at Rutgers University in the United States coordinating a study looking at the role of oxidative stress in autism. Prior to this, my work experience varied from lab-based work in protein crystallography to clinical research where I worked as a Clinical Research Associate in the pharmaceutical industry. I earned a Bachelor of Science degree from Santa Clara University in the United States.
Recent publications
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Hormone replacement therapy (conjugated oestrogens plus bazedoxifene) for post-menopausal women with symptomatic hand osteoarthritis: primary report from the HOPE-e randomised, placebo-controlled, feasibility study.
Journal article
Williams JAE. et al, (2022), Lancet rheumatol, 4, e725 - e737
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Is Treating Painful Hand Osteoarthritis with Hormone Replacement Therapy Feasible? Primary Results from a Randomised Controlled Trial in Post-menopausal Women
Conference paper
Williams J. et al, (2022), Arthritis & rheumatology, 74, 3763 - 3765