Contact information
Jennifer Williams
BSc (Hons), PHD
Clinical Research Manager
I joined NDORMS in June 2018 as the Clinical Trial Manager for the HOPE-e study. This is a feasibility study looking at whether it is acceptable for women with painful hand osteoarthritis to take an estrogen-containing therapy. We want to test whether women who take this therapy, once daily for 6 months, have reduced hand pain compared to placebo.
Prior to joining NDORMS I was a clinical trials co-ordinator for the DeNDRoN team, part of the NIHR Clinical Research Network based at the John Radcliffe Hospital. During my time in this role, I facilitated the set-up and running of several commercial CTIMPs most of which were for patients with dementia.
Before moving into the field of clinical trials, I was a scientist working in lab-based research for over 10 years. I gained my BSc (Hons) from the University of Birmingham after which I moved to London and gained my PhD in Ocular Cell Biology from UCL Institute of Ophthalmology. The majority of my publications focus on the role of the complement system in age-related macular degeneration (AMD).
Recent publications
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Hormone replacement therapy (conjugated oestrogens plus bazedoxifene) for post-menopausal women with symptomatic hand osteoarthritis: primary report from the HOPE-e randomised, placebo-controlled, feasibility study.
Journal article
Williams JAE. et al, (2022), Lancet rheumatol, 4, e725 - e737
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HAND OSTEOARTHRITIS: INVESTIGATING PAIN EFFECTS IN A RANDOMISED PLACEBO-CONTROLLED FEASIBILITY STUDY OF ESTROGEN-CONTAINING THERAPY (HOPE-E): REPORT ON THE PRIMARY FEASIBILITY OUTCOMES
Conference paper
Williams JAE. et al, (2022), Annals of the rheumatic diseases, 81, 1616 - 1617
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Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial.
Journal article
Marian IR. et al, (2021), Pilot feasibility stud, 7