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Jinsen Lu

MD.DPhil


Postdoctoral Research Associate in Single Cell and Spatial Multiomics Assay Development

Anti-Ageing Compounds and Spatial Multiomics in Bone Marrow Malignancies

Background and research

He is a qualified orthopaedic surgeon in china graduating from an 8 years bachelor-master integral surgical programme at AHMU in China. He complete my surgical resident training in 1st affiliated hospital of the university of science and technology in china with a focus on traumatic orthopaedics. He joined the group of musculoskeletal ageing and oncology led by prof. James Edwards and Claire Edwards in 2020 to study the extraskeletal effects of bisphosphonates. Then from 2024, he join the group of Udo Oppermann as a postdoctoral research associate to develop spatial single cell multiomics platform for research of multiple myeloma.

Current research focus on the following area:

1. Constructing multi-level (WGS/RNA/protein) platform with novel spatial single cell technique to study the pathology of multiple myeloma in various clinical settings.  

2. Exploring the Anti-ageing potential and subcellular mechanism of novel bisphosphonates via systemic screening, multi-omics assessment, AI-based prediction and multi-level validation.

3.AI Spatial multiomics model of bone marrow malignancies.

4. Clinical trials and epidemiological analysis of bisphosphonates on multiple non-skeletal dieseases

Collaboration:

1.Real world data, clinical trial and large omics data based analysis for anti-ageing components and bisphosphoantes.

2.Advanced spatial multiomics platform and associated AI tools development for myeloma, bone and blood malignancies.