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_{Oxford Clinical Trials Research Unit}

ABOUT US THEMES PORTFOLIO NEWS TRAINING OUR TEAM EXPLAIN INITIATIVE METHODOLOGY PATIENT AND PUBLIC INVOLVEMENT

TRIALS

PPI

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Our news

Trial shows that suture repair fails to improve digital nerve injury outcomes

11 September 2025
FORENSIC-UK opens to recruitment

10 September 2025
The GEKO study opens to recruitment

4 September 2025
Surgery to treat chronic sinus disease more effective than antibiotics

29 August 2025
The ACL STARR study opens to recruitment

2 July 2025

More news

Our training sessions

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OCTRU Extended Training Bite: SIMS Overview *online*

Tuesday, 23 September 2025, 10am to 12pm @ online
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OCTRU Training Bite: Introduction to REDCap

Thursday, 25 September 2025, 1.30pm to 2.30pm @ NOC ND08
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OCTRU New Starter Training *online*

Tuesday, 07 October 2025, 10.30am to 11.30am @ online
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OCTRU Training Bite: Patient Information Sheets (PIS) - development of good PIS *online*

Wednesday, 08 October 2025, 11.30am to 12.30pm @ online

More training

Our recent publications

The clinical effectiveness of clarithromycin versus endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps (MACRO): a pragmatic, multicentre, three-arm, randomised, placebo-controlled phase 4 trial

Philpott C. et al, (2025), Lancet, 406, 926 - 939
A 3-week pause versus continued Bruton tyrosine kinase inhibitor use during COVID-19 vaccination in individuals with chronic lymphocytic leukaemia (IMPROVE trial): a randomised, open-label, superiority trial.

Cook JA. et al, (2025), Lancet haematol, 12, e294 - e303
Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial.

Bryant RJ. et al, (2025), Lancet oncol, 26, 583 - 595
Developing generic clinical trial animated explainer videos in the UK: results of a survey and case study.

Calvert C. et al, (2025), Trials, 26

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We are open for collaborations and welcome your requests at any point.

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NIHR CTU SUPPORT

This unit receives National Institute for Health Research CTU Support Funding.
This funding has been awarded to support the unit in developing and supporting NIHR trials.