Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The 17th February saw the publication of Dr David Keene and Prof Keith Willett's paper "How effective are platelet rich plasma injections in treating musculoskeletal soft tissue injuries?" in the British Medical Journal. The article can be downloaded using the toll free link here

The paper is connected with the PATH-2 study, led by researchers in NDORMS, and forms part of a BMJ series of occasional articles that highlight areas of practice where management lacks convincing supporting evidence.

The key messages of the article include:

  • Routine use of autologous platelet-rich plasma (PRP) is not recommended as there is insufficient evidence of clinical efficacy; instead, its use should be restricted to research settings
  • Ensure patients receiving PRP are aware of the limited evidence of efficacy, so that they can make an informed decision about their care
  • Clinicians should be aware of the concentration of PRP, and yield of bioactive proteins, produced by their selected preparation device

The PATH-2 study is a randomised controlled trial to compare the effects on muscle-tendon function of a standardised PRP preparation versus dry needle injection (control) for non-operatively managed acute Achilles tendon rupture. You can read more about the trial here.

Similar stories

AVID-CC trial opens to recruitment!

OCTRU

The AVID-CC trial has received OCTRU Green Light approval and is now open to recruitment!

WHiTE Four trial results published

Hip Main OCTRU Orthopaedics and trauma Research Trauma

The results of the WHiTE Four clinical trial for the treatment of fragility hip fractures have been published in The Bone and Joint Journal.

WHiTE Four trial results!

OCTRU

The WHiTE Four trial has now published its results in The Bone & Joint journal.

FUTURE GB Trial opens to recruitment!

OCTRU

The FUTURE GB Trial has received OCTRU Green Light approval and is now open to recruitment!

ARCADIAN trial opens to recruitment!

OCTRU

The ARCADIAN trial has received OCTRU Green Light approval and has now begun to open sites to recruitment!

HOPE-e study resumes recruitment of women with painful osteoarthritis in the hand

Main OCTRU

Researchers in Oxford are looking to recruit women who have painful osteoarthritis in joints of their hands, after resuming a study that was paused due to the COVID crisis.