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The SPRAINED Study is a multi-centre observational cohort study of acute ankle sprains that present to NHS Emergency Departments. The study is validating a prognostic tool for use in Emergency Departments for patients with acute ankle sprain to identify those in whom recovery may be substantially prolonged or incomplete and additional investigations or treatment is indicated. The study was funded by the NIHR HTA (project number 13/19/06) and opened to recruitment in July 2015 to March 2016.

Recruitment was initially slow as the 10 participating sites progressively opened in the summer months of 2015. However, recruitment accelerated rapidly through autumn 2015 with all sites active and the momentum was maintained to slightly exceed our target of 675 with 682 participants recruited. The study is now in follow-up with patient reported outcomes being collected throughout 2016 at 4 weeks, 4 months, and 9 months following the patient’s ankle sprain. The final results will be available in 2017.