The World Hip Trauma Evaluation Four (WHiTE Four) study has now opened for recruitment in its first two sites (Northumbria Specialist Emergency Care Hospital in Northumberland, and John Radcliffe Hospital in Oxford). The study is a multi-centre, multi-surgeon, parallel, two arm, randomised controlled trial that will be running in 8+ hospitals in the UK. It is embedded within the WHiTE Comprehensive Cohort Study. The study includes a two-way superiority comparison between the X-Bolt Hip System (XHS) and Sliding Hip Screw fixations, and patients who present to A&E with a trochanteric fracture of the hip, who are 60 years of age and older, are eligible to participate. The trial will last a total of 38 months, with participant recruitment taking 18 months and final follow-up at 12 months post-surgery. Based upon 2013 data in the National Hip Fracture Database, the involved units perform approximately 800 of such procedures per year. The trial’s primary outcome is to quantify and draw inferences on observed differences in participants’ health status between the trial treatment groups at 4 months post-injury, and the secondary outcomes are to quantify and draw inferences on observed differences in the risk of all cause revision surgery, and in the proportion of complications/radiographic changes within the first year post-injury between the trial treatment groups.
For more information please visit https://www.ndorms.ox.ac.uk/clinical-trials/current-trials-and-studies/white