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The majority of patients with osteoarthritis present to orthopaedic surgeons seeking relief of pain and associated restoration of function. Although our understanding of the physiology of pain has improved greatly over the last 25 years there remain a number of unexplained pain-related observations in patients with osteoarthritis. The understanding of pain in osteoarthritis, its modulation and treatment is central to orthopaedic clinical practice and in this annotation we explore some of the current concepts applicable. We also introduce the concept of the 'phantom joint' as a cause for persistent pain after joint replacement.

Original publication




Journal article


The Journal of bone and joint surgery. British volume

Publication Date





280 - 287


Nuffield Department of Orthopaedic Surgery, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford OX3 7LD, UK.


Nociceptors, Humans, Osteoarthritis, Pain, Pain Measurement, Orthopedic Procedures, Arthroplasty, Replacement, Pain Threshold, Pain Management