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Autoimmune deafness represents a heterogeneous group of disorders in which there is though to be inner ear and/or middle ear damage mediated by various immunological abnormalities. We describe a patient with Wegener's granulomatosis in whom there was evidence of significant inner ear damage caused by vasculitis, which was completely reversed by cyclophosphamide and prednisolone. We propose that Wegener's granulomatosis is a cause of autoimmune deafness.

Type

Journal article

Journal

The Journal of rheumatology

Publication Date

05/1991

Volume

18

Pages

766 - 768

Addresses

Department of Rheumatology, Selly Oak Hospital, Birmingham, UK.

Keywords

Lymphocytes, Humans, Deafness, Vasculitis, Autoimmune Diseases, Cyclophosphamide, Prednisolone, Cell Movement, Adult, Ear, Inner, Male, Wegener Granulomatosis