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Autoimmune deafness represents a heterogeneous group of disorders in which there is though to be inner ear and/or middle ear damage mediated by various immunological abnormalities. We describe a patient with Wegener's granulomatosis in whom there was evidence of significant inner ear damage caused by vasculitis, which was completely reversed by cyclophosphamide and prednisolone. We propose that Wegener's granulomatosis is a cause of autoimmune deafness.


Journal article


J rheumatol

Publication Date





766 - 768


Adult, Autoimmune Diseases, Cell Movement, Cyclophosphamide, Deafness, Ear, Inner, Granulomatosis with Polyangiitis, Humans, Lymphocytes, Male, Prednisolone, Vasculitis